Cajanuslactone, a new coumarin with anti-bacterial activity from pigeon pea [Cajanus cajan (L.) Millsp.] leaves

Kong, Yu; Fu, Yujie; Zu, Yuangang; Chang, Fang-Rong; Chen, Yung-Husan; Liu, Xiaolei; Stelten, Johannes; Schiebel, Hans‐Martin

doi:10.1016/j.foodchem.2010.01.062

Cited by 100 publications

(58 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is widely cultivated in Poteran Island, Madura for its edible seeds. Chemical constituent investigations have indicated that Cajanus cajan leaves are rich of flavonoids such as pinostrobin, longistilins [4], cajachalcone [5], coumarin and stilbenes [6], which are considered responsible for the beneficial efficacies of C. cajan leaves on human health [7][8]. The objective of the present study was to evaluate the compounds potential of methanol extract of leaves, stems and roots of the plant and their antioxidant activities.…”

Section: Introductionmentioning

confidence: 99%

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

2018

View full text Add to dashboard Cite

New Prenylated stilbene derivatives, 3-hydroxy-4-prenyl-5-methoxy-stilbene acid (1) and 5,4'-dihydroxy-3-methoxy-2-prenyl-stilbene (2) Millsp.; stilben terprenilasi; antioksidan;2, ABSTRAK Dua turunan stilben terprenilasi baru, Asam 3-hidroksi-4-prenil-5-metoksi-stilben (1) dan 5,4'-dihidroksi-3-metoksi-2-prenil-stilben (2) telah berhasil diisolasi dari ekstrak metanol tumbuhan kacang kayu (Cajanus cajan (L.) Millsp.) anggota famili fabaceae. Tujuan penelitian ini adalah untuk mengetahui potensi senyawa-senyawa tersebut sebagai antioksidan secara in vitro menggunakan radikal 2,2-difenil-1-pikrihidrazil (DPPH

show abstract

Section: Introductionmentioning

confidence: 99%

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

2018

View full text Add to dashboard Cite

show abstract

“…Derivatives of neoavonoids, also named 4-arylcoumarins, are widespread in nature and have possessed a broad spectrum of biological activities 1 including antioxidant, 2-4 antidiabetic, 5 cytotoxic, [6][7][8] antimicrobial, [9][10][11] anti-inammatory, 12 antiprotozoal [13][14][15] and estrogenic 16 activities. Korec and co-workers 17 reported that oral administration of an extract prepared from a commercial mixture of the stem barks of H. latiora and E. caribaeum (CM) of uncertain origin decreased glucose levels in streptozotocin (STZ)-diabetic mice during short term experiments in 2000.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and biological evaluation of novel neoflavonoid derivatives as potential antidiabetic agents

Wang

et al. 2017

RSC Adv.

View full text Add to dashboard Cite

Various substituted neoflavonoid derivatives were synthesized using sulfated montmorillonite K-10 as a catalyst. This method is environmental friendly, sustainable and economical, convenient in isolation and purification processes, with little byproducts, using earth-abundant catalysts and has relatively high yield. Those neoflavonoid derivatives were screened for antioxidant, a-glucosidase inhibitory, aldose reductase 2 (ALR2) inhibitory and advanced glycation end-product formation inhibitory effects. Most compounds exhibited significant antioxidant and advanced glycation end-product (AGE) formation inhibitory activities. It was interesting to note that out of thirty compounds, 8k and 8l were found to have greater ALR2 inhibitory activity than the standard drug quercetin. The pharmacological studies suggested neoflavonoid with adjacent 7,8-dihydroxy groups were more effective in inhibiting ALR2. Antidiabetic activity studies had shown that compounds 8l and 8m were equipotent to the standard drug glibenclamide in vivo. In summary, the target compound 8l provided a potential drug design concept for the development of therapeutic or prophylactic agents of diabetes and diabetes complications.

show abstract

“…Pigeon pea (Cajanus cajan) is one of the most valuable perennial leguminous food crops in Asia, Africa and some regions of South America, having an important role in the field of agriculture and food (Kong et al, 2010). As a tropical grain-legume, it has demonstrated high tolerance to drought stress (Otieno et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Molecular cloning of an S-adenosylmethionine synthase gene from pigeon pea (Cajanus cajan) and its expression analysis under arbuscularmycorrhizae fungi colonization and drought stress

Qiao

Zhang

Wen

2017

View full text Add to dashboard Cite

An S-adenosylmethionine synthase (SAMS) gene associated with the drought responsiveness was isolated and characterized from pigeon pea. It was designated CcSAMS and contained an open reading frame of 1,182 bp, which encoded 394 amino acid residues. Sequence analysis of the cloned cDNA showed 94% identity with SAMS from other plant species, suggesting that this gene was considerably conserved in plants. Gene expression analysis demonstrated that CcSAMS was highly expressed in the leaves of AM-colonized plants, irrespective of exposure to either drought or drought-free. Rather, the expression levels of AM plants were significantly higher than that of NAM plants as subjected to drought stress. Therefore, AM symbiosis might enhance the expression of CcSAMS, and the elevated tolerance of AM-colonized pigeon pea to drought-stress was at least partially ascribed to the overexpression of SAMS gene.

show abstract

Cajanuslactone, a new coumarin with anti-bacterial activity from pigeon pea [Cajanus cajan (L.) Millsp.] leaves

Cited by 100 publications

References 27 publications

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

New Prenylated Stilbenes and Antioxidant Activities of <i>Cajanus cajan</i> (L.) Millsp. (Pigeon pea)

Synthesis and biological evaluation of novel neoflavonoid derivatives as potential antidiabetic agents

Molecular cloning of an S-adenosylmethionine synthase gene from pigeon pea (Cajanus cajan) and its expression analysis under arbuscularmycorrhizae fungi colonization and drought stress

Contact Info

Product

Resources

About