“…The study of the system response to a local perturbation is particularly relevant to complex and heterogeneous media, such as glasses, gels, and many biological systems. Experimentally, the microscopic probe can be driven externally by using magnetic or optical tweezers; such an experimental technique, called active micro-rheology, (where the term "active" emphasizes that the tracer is not in equilibrium with the environment but rather induces some micro-structural changes in the host medium), has been successfully applied to probe the micro-rheological properties of a variety of different systems (see, e.g., [1,2] for recent reviews), including living cells [3], colloidal suspensions [4], soft glassy materials [5,6], and granular media [7][8][9][10], to name but a few.…”