Caffeine use and plasma concentrations in psychiatric outpatients

Lande, R. Gregory; Labbate, Lawrence A.

doi:10.1002/(sici)1520-6394(1998)7:3<130::aid-da6>3.0.co;2-f

Cited by 6 publications

(1 citation statement)

References 14 publications

(22 reference statements)

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“…(6) Daily Caffeine Consumption (DCC) questionnaire: this questionnaire-designed by the authors (available at request)-consists of the most often consumed foods/drinks/drugs containing caffeine. Conventional estimates of the amount of caffeine contained in various foods/beverages [Lande and Labbate, 1998;Sadock and Sadock, 2003], and personal communication with companies producing some of them were used for the estimation of each patient's DCC. Taking into account the various categorizations of patients according to their DCC [Dager et al, 1999;Mathew and Wilson, 1990;Zoellner and Craske, 1999], the following categorization was used: (1) None: DCC 5 0 mg (2) Low: 0 mgoDCCr100 mg (3) Moderate: 100 mgoDCC r300 mg (4) High: DCC4300 mg.…”

Section: Psychometric Evaluationsmentioning

confidence: 99%

Caffeine challenge in patients with panic disorder: baseline differences between those who panic and those who do not

et al. 2008

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A proportion of patients with panic disorder (PD) display an increased sensitivity to the anxiogenic/panicogenic properties of caffeine. The aim of this study is to identify probable baseline differences between PD patients who panic and those who do not, after caffeine administration. In a randomized, double-blind, cross-over experiment performed in two occasions 3-7 days apart, 200 and 400 mg of caffeine, respectively, were administered in a coffee form to 23 patients with PD with or without Agoraphobia. Evaluations included the State-Trait Anxiety Inventory, the DSM-IV 'panic attack' symptoms (visual analogue scale form), the Symptom Checklist-90-Revised (SCL-90-R), as well as breath-holding (BH) duration, heartbeat perception accuracy and heart rate. Only those patients who did not present a panic attack after both challenges ('no panic group', N=14, 66.7%), and those who presented a panic attack after at least one challenge ('panic group', n=7, 33.3%) were included in the analysis. The panickers, compared to the non-panickers, presented at baseline: significantly higher total score of the SCL-90-R; significantly higher scores on all the SCL-90-R clusters of symptoms, except that of 'paranoid ideation'; significantly lower BH duration. The present preliminary findings indicate that PD patients who panic after a 200 mg or a 400 mg caffeine challenge, compared to the PD patients who do not panic after both of these challenges, may present at baseline significantly higher non-specific general psychopathology--as reflected in the SCL-90-R--and significantly shorter BH duration.

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Section: Psychometric Evaluationsmentioning

confidence: 99%