Caffeine supplementation as part of enhanced recovery after surgery pathways: a narrative review of the evidence and knowledge gaps

Pleticha, Josef; Niesen, Adam D.; Kopp, Sandra L.; Johnson, Rebecca L.

doi:10.1007/s12630-021-01943-1

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…There are no randomized, controlled, multicenter studies evaluating the administration of caffeine in the perioperative period. The results of the few studies conducted suggest that the administration of caffeine in the perioperative period reduces the incidence of headache associated with caffeine withdrawal [ 73 ]. Hampl et al studied 40 patients who underwent minor surgery.…”

Section: The Role Of Caffeine Withdrawal In Provoking Headachesmentioning

confidence: 99%

Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature

et al. 2023

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Consumption of caffeine in the diet, both daily and occasional, has a significant biological effect on the nervous system. Caffeine, through various and not yet fully investigated mechanisms, affects headaches. This is especially noticeable in migraine. In other headaches such as hypnic headache, post-dural puncture headache and spontaneous intracranial hypotension, caffeine is an important therapeutic agent. In turn, abrupt discontinuation of chronically used caffeine can cause caffeine-withdrawal headache. Caffeine can both relieve and trigger headaches.

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Section: The Role Of Caffeine Withdrawal In Provoking Headachesmentioning

confidence: 99%

Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature

et al. 2023

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Incidence and Factors Associated with Postoperative Headache among Adult Elective Surgical Patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2022

Zegeye,

Ahmed,

Aytolign

et al. 2024

Preprint

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Background Postoperative headache is a medical condition that has a strong association with future recurrent and chronic headache, higher morbidity and mortality, extended hospital stays, poor quality of life and high financial burden. Despite, having these consequences, there are limited studies regarding the incidence and associated factors of postoperative headache. Objective The objective of this study was to assess the incidence and associated factors of postoperative headache among adult elective surgical patients at University of Gondar Comprehensive Specialized Hospital Northwest Ethiopia, April 9 to 20 June 2022. Methods An institution -based follow- up study was conducted from April 9 to June 20 2022, at University of Gondar Comprehensive Specialized Hospital, after approval of ethical committee, Consecutively 424 patients were included. Postoperative headache was measured based on patient interview and the response was dichotomized as present or absent. Data were collected through chart review as well as patient interviews using a questionnaire. Data entered in to epidata 4.6.0 and statistical analysis was performed using stata version 14.01 software. Descriptive statistics was conducted to summarize patient’s information and to determine the incidence of postoperative headache. Binary logistic regression was conducted to identify factors associated with postoperative headache. Variables with P-value < 0.05 were considered statistically significant. Results The overall incidence of postoperative headache in the first three postoperative days was 54.3% and the response rate was 99%. Previous history of headache (AOR = 4.83, CI = 2.42 9.73), prolonged fasting (AOR = 2.28, CI = 1.44–3.60), general anesthesia (AOR = 1.96, CI = 1.25 3.07), intraoperative hypotension (AOR = 1.74, CI = 1.06–2.88), female gender (AOR = 1.62,CI = 1.06–2.54) and caffeine consumption(AOR = 1.60,CI = 1.02–2.52) were significantly associated with postoperative headache and most of patients (39%) were experienced moderate headache Conclusion and recommendations: According to the findings of our study, more than half of surgical patients suffered from postoperative headache. Use of general anesthesia techniques, having history of headache, being female, intraoperative hypotension, caffeine consumption and having prolonged preoperative fasting were strongly associated with postoperative headache. The problem needs regular assessment and treatment.

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Caffeine supplementation as part of enhanced recovery after surgery pathways: a narrative review of the evidence and knowledge gaps

Cited by 2 publications

References 21 publications

Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature

Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature

Incidence and Factors Associated with Postoperative Headache among Adult Elective Surgical Patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2022

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