Caffeine challenge in insomniac patients after total sleep deprivation☆

Salín-Pascual, Rafael J.; Valencia‐Flores, Matilde; Campos, Rosa M.; Castaño, Ana; Shiromani, Priyattam J.

doi:10.1016/j.sleep.2005.06.008

Cited by 19 publications

(9 citation statements)

References 22 publications

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“…Coffee, which comprises a large part of the global beverage market, exhibits both harmful and beneficial effects. It has been associated with a decrease in chronic disease, such as type 2 diabetes [8], but its harmful associations include a higher incidence of cerebral infarction [9], and its withdrawal symptoms include fatigue and headache [10]. …”

Section: Introductionmentioning

confidence: 99%

Beverage Intake, Smoking Behavior, and Alcohol Consumption in Contemporary China—A Cross-Sectional Analysis from the 2011 China Health and Nutrition Survey

Lee

Wang

Chiang

et al. 2017

IJERPH

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Chinese residents enjoy various types of beverages in their daily life. With the rapid Westernization of contemporary China, several adverse health concerns—such as diabetes linked to sweetened beverages—have emerged. Until now, no research that examines associations between beverage consumption and smoking/drinking behaviors has been made available, despite the large Chinese populations partaking in such activities. We conducted a cross-sectional study to explore the association between beverage intake frequencies and smoking/drinking behaviors in 12,634 adult respondents who participated in the latest wave (2011) of the China Health and Nutrition Survey (CHNS). Further, we applied Tukey’s Honest Significance test for pairwise comparisons. We defined the consumption categories as daily (at least one serving per day), weekly (less than one serving per day, at least one serving per week), monthly (less than one serving per week, at least one serving per month), and less than monthly or none—for sweetened beverage, water, tea, and coffee consumptions. The data showed that both tea and sweetened beverages are associated with smoking/drinking behaviors. Compared to respondents who consume tea and sweetened beverages daily, the odds of smoking behaviors are lower for those who consume such beverages less frequently. Further policy implications are discussed, including higher taxes on sweetened beverages and lessons from other countries.

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Section: Introductionmentioning

confidence: 99%

Beverage Intake, Smoking Behavior, and Alcohol Consumption in Contemporary China—A Cross-Sectional Analysis from the 2011 China Health and Nutrition Survey

Lee

Wang

Chiang

et al. 2017

IJERPH

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“…However, chronic caffeine use may lead to fewer sleep-related complaints in users [12]. This use of caffeine, especially in middle-aged adults, as seen here and previously [13,15], may make users vulnerable to the circadian wake-promoting signal during daytime and also lead to sleep fragmentation [16]. Sleep fragmentation may be clinically manifested as NRS.…”

Section: Discussionmentioning

confidence: 91%

Caffeine consumption, insomnia, and sleep duration: Results from a nationally representative sample

Chaudhary¹,

Grandner

Jackson

et al. 2016

Nutrition

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Objective: Insomnia symptoms have been individually associated with both caffeine consumption and sleep duration abnormalities in prior studies. The goal of this study was to determine whether caffeine consumption was associated with insomnia symptoms from a population perspective and whether this relationship depended on habitual sleep duration. Methods: Data were extracted from the 2007–2008 National Health and Nutritional Examination Survey (N = 4730). Caffeine consumption was quantified as mg/d from 2 typical days of use, 7 to 10 d apart. Insomnia symptoms were evaluated using frequencies of difficulty falling asleep (DFA), difficulty staying asleep (DSA), non-restorative sleep (NRS), and daytime sleepiness (DS). Habitual sleep duration was assessed as the hours of sleep obtained on a typical night. Binomial logistic regression analysis evaluated the relationships of individual insomnia and sleepiness symptoms (DFA, DSA, NRS, and DS) with caffeine consumption and sleep duration variables, after adjusting for covariates. Results: The mean ± SD caffeine consumption was 176.6 ± 201 mg/d. Mean habitual sleep duration was 6.8 ± 1.4 h. Insomnia symptoms were prevalent in 19.1% to 28.4% of the respondents. Although caffeine consumption was associated with all insomnia symptoms in the unadjusted models, the adjusted models demonstrated a trend toward significance with DSA. Sleep duration was inversely associated with the insomnia symptoms in unadjusted and adjusted analysis. Finally, NRS was associated with an interaction between increased caffeine consumption and sleep duration. Conclusion: The association between caffeine use and insomnia symptoms depends on habitual sleep duration at a population level.

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“…Similarly blockade of the adenosine A2A receptors may prevent the sleep-active neurons in the preoptic area from becoming active [55]. The effects of caffeine on sleep architecture have been shown in normal volunteers [48,56] and insomniac patients [57], caffeine is capable of antagonizing the cognitive impairment produced by prolonged sleep deprivation [58]. In rats, we determined that a reduction in sensitivity or number of adenosine receptors might contribute to the decline in sleep drive with aging [55,59].…”

Section: Adenosine and Caffeine In Parkinson Diseasementioning

confidence: 94%

Sleep, Adenosine and Caffeine as Tools for The Early Diagnosis of Parkinson Disease

Salín-Pascual¹

2012

TOSLPJ

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The information that has developed regarding Parkinson's Disease (PD) allowed to understand that there is a period of this disease, perhaps at least a decade, in which the classical features of PD are not detected as such, however, there are evidence of a series of non-motor manifestations, among which are: anosmia, constipation, psychiatric disorders such as major depression, generalized anxiety, and rapid eye movement sleep behavior disorder (RBD). On the other hand the understanding of physiological mechanisms of sleep-wake cycle, have become remarkable tools to explore neurological and psychiatric disorders and complemented the information and treatments for those disorders. There is evidence that RBD can occur in half of people who will develop PD, about 10 year letter. The role of adenosine in sleep and caffeine intolerance is other aspects that are evident in the relation between PD and sleep. The detection of PD in early stages, may allow the implementation of the type of therapeutic strategies for neuroprotection. The general goal would be delay or reduce the clinical manifestations of PD in some patients.

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Caffeine challenge in insomniac patients after total sleep deprivation☆

Cited by 19 publications

References 22 publications

Beverage Intake, Smoking Behavior, and Alcohol Consumption in Contemporary China—A Cross-Sectional Analysis from the 2011 China Health and Nutrition Survey

Beverage Intake, Smoking Behavior, and Alcohol Consumption in Contemporary China—A Cross-Sectional Analysis from the 2011 China Health and Nutrition Survey

Caffeine consumption, insomnia, and sleep duration: Results from a nationally representative sample

Sleep, Adenosine and Caffeine as Tools for The Early Diagnosis of Parkinson Disease

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