2001
DOI: 10.3177/jnsv.47.139
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Caffeine as a Lipolytic Food Component Increases Endurance Performance in Rats and Athletes.

Abstract: SummaryCaffeine is one of the famous ergogenic aids in the athletic field. Caffeine has been known to stimulate lipolysis that spares stored glycogen utilization during moderate intensity exercise. Therefore, we investigated the effects of caffeine ingestion on exercise per formance in rats and athletes. Rats were administered the caffeine (6mg/kg) 1h prior to the exercise then were run on a treadmill at a speed of 20m/min. They were decapitated at 0min, 30min, 60min of exercise, and exhausted time point. Huma… Show more

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Cited by 68 publications
(68 citation statements)
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“…Further studies are required to investigate whether caffeine can be utilized to improve the physical performance of elderly citizens. fatigue; perceived exertion; postural stability; elderly CAFFEINE INGESTION INCREASES the endurance of young people exercising at 60 -85% of their maximal oxygen uptake (12,13,38). It also seems to improve endurance as measured by repeated submaximal isometric contraction (34) and decreases the rate of perceived exertion during exercise (6, 9, 37).…”
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confidence: 99%
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“…Further studies are required to investigate whether caffeine can be utilized to improve the physical performance of elderly citizens. fatigue; perceived exertion; postural stability; elderly CAFFEINE INGESTION INCREASES the endurance of young people exercising at 60 -85% of their maximal oxygen uptake (12,13,38). It also seems to improve endurance as measured by repeated submaximal isometric contraction (34) and decreases the rate of perceived exertion during exercise (6, 9, 37).…”
mentioning
confidence: 99%
“…CAFFEINE INGESTION INCREASES the endurance of young people exercising at 60 -85% of their maximal oxygen uptake (12,13,38). It also seems to improve endurance as measured by repeated submaximal isometric contraction (34) and decreases the rate of perceived exertion during exercise (6,9,37).…”
mentioning
confidence: 99%
“…Caffeine acts as phosphodiesterase (PDE) inhibitor that causes an increase in cyclic adenosine monophosphate (cAMP) in the brain and leads to stimulation of catecholamines (i.e., epinephrine) [25,26]. This elevation in epinephrine levels [27] would, in turn, improve performance by delaying carbohydrate utilization and preserving muscle glycogen content and it Cause a greater stimulation of lipolysis during exercise and a greater release of circulating FFAs into the blood stream [28]. Also this potential performance-enhancing mechanism may be particularly relevant for liver (Bischof et al 2001) glycogen stores [29].…”
Section: Discussionmentioning
confidence: 99%
“…6,7) During in vivo screening for endurance capacity, coffee was found to have a marked stimulatory effect on exercise tolerance in humans 3,4) and animal models. 5,8) Although the ergogenic activity of coffee is attributed mainly to caffeine, coffee is also one of the main natural sources of 3,4-DA, a compound that has not been tested in relation to its effect on exercise tolerance.…”
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confidence: 99%
“…2) It is recognized that 3,4-DA has several pharmacological properties, including antioxidant, 3,4) anti-inflammatory, 5) and immunomodulatory 6) activities. At a concentration of 10 mM, 3,4-DA completely blocks the production of reactive oxygen species (ROS) in human neutrophils and the xanthine oxidase system.…”
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confidence: 99%