Caffeic Acid Activity Against Clostridium botulinum Spores

Abstract

Caffeic acid (CA) is widely distributed among higher fruits and vegetables. While CA has antimicrobial activity, little information exists on its utility as a food additive. As such, CA was tested for activity against Clostridium botulinum spores. At 0.78 and 3.25 mM, CA inhibited germination for 6 and 24 hr, respectively, with >lOO mM required to render spores nonviable. CA concentrations 5: 50mM reduced 80°C spore thermal resistance. Sporostatic activity was retained when tested in commercial meat broths, and 5.0 mM CA delayed toxigenesis. Caffeic acid has potential as a food additive to inhibit growth of C. botulinurn, and reduce thermal processing requirements of heat sensitive foods.

The influence of pH on the thermal stability of 5-O-caffeoylquinic acids in aqueous solutions

“…5,6,7). This shape of the relationships can be explained by the occurrence of two competitive reactions at simultaneous degradation of Fig.…”

“…Potential uses of 5-CQA are suggested in pharmaceuticals, dietary (foodstuVs, food additives), and cosmetics due to its recently discovered biomedical activity [3][4][5][6][7][8][9]. This Wnding caused new interest in 5-CQA properties, its isomers, and its natural occurrence.…”

Synthesis and leishmanicidal activity of cinnamic acid esters: structure–activity relationship

“…Caffeic acid (1), 3,4-dihydroxy cinnamic acid, and its esters derivatives exhibit a broad spectrum of biological activities, including anti-inflammatory (Jayaprakasam et al, 2006;Da Cunha et al, 2004), antimicrobial (Almajano et al, 2007;Noriaki et al, 2005;King et al,1999;Valenta et al, 1998;Bowles et al, 1994) antioxidant (Hung et al, 2005;Noriaki et al, 2005;Kikuzaki et al,. 2002;Son et al, 2002;Rajan et al, 2001) and anticarcinogenic effects (De et.…”

Evaluation of Chlorophyll Content, Antioxidant Activity and Phenolic Compounds in the Seedlings of Rice-type Tartary Buckwheat

“…Rutin is also known to have anti-inflammatory, anticarcinogenic effects (Liu et al, 2008) and is effective for preventing hemorrhagic disease and arteriosclerosis (Fabjan et al, 2003). Other bioactive compounds like quercetin and chlorogenic acid present in buckwheat have been identified as strong antioxidants, antimicrobial, antifungal (Bowels and Miller, 1994), anti-angiogenesis and anticancer (Jackson and Venema, 2006) agent.…”