“…While there are limitations such as lack of specific organ equivalents, a smaller immune response system, and large differences in overall lifespan, C. elegans allows medium-throughput whole organism-level assays with multiple endpoints (eg, development, reproduction, feeding, lifespan, locomotion) (15). Worms have been used to assess the toxicity of terrestrial environmental samples (eg, soils, sludge, river sediments (17,18), pesticides (eg, Glyphosate, Paraquat, Endosulfan and Dichlorvos for neurotoxicity, DNA damage, sterility and embryonic lethality) (19), metal toxicity (eg, Ag, Cd, Pb, Fe), lifespan, fertility, growth (20), nanoparticles (21), drugs (22), toxins (eg, nicotine) (23–25), as well as other bioreactive molecules including NaAsO 2 , NaF, caffeine, and DMSO (26). While airborne bacteria have been tested in C. elegans (17), its responses to TRAP have not been studied.…”