J. Neurosci. Res. volume 87, issue 1, P228-237 2009 DOI: 10.1002/jnr.21830 View full text
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Massimo Gulisano, Stefania Pacini, Tiziana Punzi, Gabriele Morucci, Sara Quagliata, Giovanni Delfino, Erica Sarchielli, Mirca Marini, Gabriella B. Vannelli

Abstract: Cadmium is an environmental pollutant inducing numerous pathological effects, including neurological disorders and brain diseases. However, little is known about the molecular mechanisms of cadmium in affecting neurons and in inducing neurotoxicity in the development of the human brain. We have recently established, cloned, and propagated in vitro a primary long-term cell culture (FNC-B4) obtained from the human fetal olfactory neuroepithelium. In the present study, we show that different concentrations of cad…

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