“…Studies by other groups have established the importance of additional cadherins besides N‐cadherin, such as E‐cadherin and Cadherin‐6B, in premigratory and migratory NC throughout the cranial and trunk axial levels of the chick (Coles, Taneyhill, & Bronner‐Fraser, ; Dady et al, ; Dady & Duband, ; Lee et al, ; Nakagawa & Takeichi, ; Taneyhill, Coles, & Bronner‐Fraser, ). Through immunohistochemical and in situ hybridization analyzes, Dady and Duband (Dady & Duband, ; Dady et al, ) demonstrated that E‐cadherin and Cadherin‐6B are expressed in the proper spatio‐temporal pattern to play a role in the specification of the NC and defining the premigratory NC domain (Dady & Duband, ), including in the head and anterior and mid trunk. Furthermore, these authors demonstrate that Cadherin‐6B expression, but not N‐cadherin, defines the premigratory NC domain in these truncal regions, with delaminating cells here devoid of Cadherin‐6B , N‐cadherin, and E‐cadherin, but later expressing Cadherin‐7 during migration.…”