Cabazitaxel followed by androgen deprivation therapy (ADT) significantly improves time to progression in patients with newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): A randomized, open label, phase III, multicenter trial

Hormone therapy of metastatic prostate cancer (mPC) has been the “golden standard” of treatment since 1941. However, survival rates in patients with this pathology have remained low. Based on the results of newer studies, early start of docetaxel chemotherapy or antiandrogen abiraterone therapy in combination with standard hormone therapy allows to significantly increase survival of patients with mPC. In this review, data from these studies and advisability of docetaxel and abiraterone at the 1st line therapy of mPC are discussed.

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Current approaches to selection of the 1st line therapy in patients with metastatic hormone-sensitive prostate cancer

Alekseev¹,

Andrianov²,

Каприн³

2018

Cancer Urology

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Cabazitaxel followed by androgen deprivation therapy (ADT) significantly improves time to progression in patients with newly diagnosed metastatic hormone sensitive prostate cancer (mHSPC): A randomized, open label, phase III, multicenter trial

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Current approaches to selection of the 1st line therapy in patients with metastatic hormone-sensitive prostate cancer

Current approaches to selection of the 1st line therapy in patients with metastatic hormone-sensitive prostate cancer

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