1998
DOI: 10.1002/(sici)1097-4547(19980901)53:5<626::aid-jnr12>3.0.co;2-z
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Ca2+ changes and86Rb efflux activated by hyposmolarity in cerebellar granule neurons

Abstract: Hyposmotic swelling increased 86Rb release in cultured cerebellar granule neurons (1 day in vitro [DIV]) with a magnitude related to the change in osmolarity. 86Rb release was partially blocked by quinidine, Ba2+, and Cs+ but not by TEA, 4-AP, or Gd3+. 86Rb efflux decreased in Cl(-)-depleted cells or cells treated with DDF or DIDS, suggesting an interconnection between Cl- and K+ fluxes. Swelling induced a substantial increase in [Ca2+]i to which both external and internal sources contribute. However, 86Rb eff… Show more

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Cited by 10 publications
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