Abstract:The formation of the CSb-9 complex on the outer membrane of complement-sensitive cells ofEscherichia coli results in inhibition of inner membrane function and the death of the cell. Cells bearing a precursor of the C5b-9 site, the C5b-8 complex, suffer no loss in viability. Antibiotic-sensitive, complement-sensitive donor cells bearing precursor C5b-8 complexes were incubated with equal numbers of antibiotic-resistant, complementsensitive acceptor cells that had not been exposed to a complement source. This ce… Show more
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