C2-Selective silylation of pyridines by a rhodium–aluminum complex

Abstract

We have developed a C2-selective mono-silylation of a variety of pyridines using a Rh-Al complex. Both the site- and mono-selectivity are controlled via the pyridine coordination to the Lewis- acidic...

Bonding and Reactivity of a Pair of Neutral and Cationic Heterobimetallic RuZn2 Complexes

“…Heterobimetallic complexes comprised of a transition metal (TM) and a main group metal (MGM) are the focus of considerable interest − because of the possibility that the disparate chemistry of the two partners could combine cooperatively to bring about the novel stoichiometric and/or catalytic activation of small molecules. − In one recent example, shown in Scheme a, the challenging C–O activation of an anisole takes place across the Rh–Al bond of complex I to afford II , which upon addition of a silane, mediates catalytic C–O bond reduction . Complex I represents one class of heterobimetallic complexes in which the MGM forms part of a multidentate ligand on the TM center .…”

Diverse reactivity of an iron–aluminium complex with substituted pyridines

“…1 In the last few years new strategies have emerged for the C-H activation of pyridines that are based on cooperative action of transition metal and main group elements contained within a single reactive species. [2][3][4][5][6][7][8][9][10][11][12] Very recently, our group reported a well-defined Fe-Al complex that is capable of selectively breaking the sp 2 C-H bond of pyridine (Fig. 1).…”

Bimetallic anchoring catalysis for C-H and C-C activation

“…In addition, they found that a similar catalyst can also effectively facilitate a C2-H silylation of pyridines, providing a series of silylated heterocyles in up to 94% yield (Scheme 20) [31].…”