C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty

Тарасов, Д А; Лычагин, А.В.; Yavorovkiy, Andrei G; Lipina, Marina; Tarasova, I.A.

doi:10.1007/s00264-020-04551-8

International Orthopaedics (SICOT)

2020

DOI: 10.1007/s00264-020-04551-8

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C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty

Д А Тарасов

А.В. Лычагин

Andrei G Yavorovkiy

et al.

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Cited by 3 publications

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“…We published also papers related to the use of drugs or medications before or after surgery as well as regional anaesthetic blocks [8][9][10][11]. However, the most read and cited borderline papers are dedicated to pain management and blood loss as well as the outcome studies in controversial subjects [12][13][14][15]. Some of the published papers were dedicated to analgesia and anaesthesia.…”

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confidence: 99%

About anesthesiology and surgery: analgesia, anaesthesia, and non-surgical papers published in journals of surgery

Scarlat

Mavrogenis

2021

International Orthopaedics (SICOT)

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Subjects treated in a general orthopaedic publication are innumerable. Some themes could not be included in a very specialized journal or in a technical publication because they treat "borderline" subjects such as the biology of healing in tissues, patient-related outcomes in a specific procedure, or pain management. Other papers that have a difficulty in finding a place are participation of vitamins or regimes in healing, education in preparation of patients for a specialized procedure such as joint replacement, and doctor's experience in introducing new procedures.We published many such controversial subjects related to orthopaedics and conjunctive tissue [1-3]. We published papers dealing with the use of specific molecules like tranexamic acid during surgery [4][5][6][7]. We published also papers related to the use of drugs or medications before or after surgery as well as regional anaesthetic blocks [8][9][10][11]. However, the most read and cited borderline papers are dedicated to pain management and blood loss as well as the outcome studies in controversial subjects [12][13][14][15]. Some of the published papers were dedicated to analgesia and anaesthesia. For millennia, pain was a major subject for both patients and doctors and modern anaesthesia realized unbelievable progress in managing pre-operative and postoperative care as well as the realization of surgery "per se" [16,17]. No surgery without anaesthesia. The surgical team includes as pre-requisite the presence of a specialized anesthesiologist doctor or assistant. Difficult cases are managed correctly with pre-operative and post-operative protocols. Many patients are old, presenting comorbidities and chronic treatments such as anticoagulants or respiratory medication. Patients become more and more demanding and the cases become more complex and difficult. Is it reasonable to refuse

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mentioning

confidence: 99%

About anesthesiology and surgery: analgesia, anaesthesia, and non-surgical papers published in journals of surgery

Scarlat

Mavrogenis

2021

International Orthopaedics (SICOT)

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C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty: several questions

Wang

2020

International Orthopaedics (SICOT)

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Effectiveness and safety of auricular acupuncture on adjuvant analgesia in patients with total knee arthroplasty: a randomized sham-controlled trial

Zhang,

Chen,

et al. 2024

Front. Neurol.

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ObjectiveThis study aimed to evaluate the effectiveness and safety of auricular acupuncture (AA) on postoperative analgesia, the degree of postoperative nausea, and the effect of inflammation after total knee arthroplasty (TKA).MethodsThis was a single-center, placebo-controlled, randomized clinical trial. In total, 96 patients were randomly divided into an AA group with an indwelling intradermal needle (n = 48) and a sham auricular acupuncture (SAA) group with a non-penetrating placebo needle (n = 48). Intra-spinal anesthesia was adopted in both groups during surgery, and an epidural analgesic pump was implanted after surgery for 48 h. The primary outcome was the post-surgery visual analog score (VAS) of resting and movement states (at 6, 12 h and 1, 2, 3, 5, and 7 days). The secondary outcomes included additional doses of analgesic injection during the treatment, C-reactive protein (CRP) levels, erythrocyte sedimentation rate (ESR), and white blood cell (WBC) count on the 1st, 3rd, and 7th day after the operation, nausea on the 1st, 2nd, and 3rd day after the operation, the Hospital for Special Surgery Knee Score (HSS) on the 2nd and 12th week after the operation, and adverse events.ResultsThe VAS in the AA group at 6 h, 12 h, 2, 3, and 5 days after surgery were lower than those of the SAA group (p < 0.05). Among the secondary outcomes, the total dose of additional analgesic injection after surgery in the AA group was lower than that in the SAA group (p < 0.05). The serum CRP on the 1st day after operation in the AA group was lower than that in the SAA group (p < 0.05). The degree of nausea on 2nd day after surgery in the AA group was lower than that in the SAA group (p < 0.05). There was no significant difference in other outcomes (p > 0.05).ConclusionIn this study, AA was shown to be an effective and safe complementary and alternative therapy for pain relief after TKA, which was able to reduce the total postoperative dose of additional painkillers, decrease serum CRP 1 day after surgery, and improve the degree of postoperative nausea.Clinical trial registrationwww.chictr.org.cn, ChiCTR2100054403.

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C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty

Cited by 3 publications

References 35 publications

About anesthesiology and surgery: analgesia, anaesthesia, and non-surgical papers published in journals of surgery

About anesthesiology and surgery: analgesia, anaesthesia, and non-surgical papers published in journals of surgery

C-reactive protein as marker of post-operative analgesic quality after primary total knee arthroplasty: several questions

Effectiveness and safety of auricular acupuncture on adjuvant analgesia in patients with total knee arthroplasty: a randomized sham-controlled trial

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