C Inner Ear Pathology following Maternal Rubella

Challenges in management of childhood sensorineural hearing loss in sub-Saharan Africa, Nigeria

“…In mumps, the abnormality is usually unilateral and limited to the membranous part of the cochlear with dilatation of the cochlear duct and saccule as in Scheibe deformity [10]. However, deafness due to other viruses, such as common cold and influenza have been documented [11,24]. Rubella has been reported to cause anatomic and teratogenic anomalies ranging from complete absence of the inner ear to mondini deformity [12,13,22,23].…”

“…Rubella has been reported to cause anatomic and teratogenic anomalies ranging from complete absence of the inner ear to mondini deformity [12,13,22,23]. Sensorineural hearing loss secondary to longstanding otitis media was reported to be due to extension of infection through the cochlear aqueduct or internal auditory meatus or erosion of the labyrinth by associated, acquired or congenital cholesteatoma [14,15,24,25]. The cases in which there were no identifiable aetiologic factor may be due to a progressive hereditary deafness.…”

Cochleo-Saccular Degeneration in One of Three Sisters with Hereditary Deafness, Absent Gastric Motility, Small Bowel Diverticulitis and Progressive Sensory Neuropathy

“…Cochleo-saccular degeneration occurs as a result of developmental defects (Schuknecht et a l, 1965) aging and infection such as maternal rubella (Lindsay et al, 1953;Alford, 1968). The endorgans of utricle and semicircular canals are morphologically and functionally not involved.…”

Sudden Deafness Due to Virus Infection

“…Inner-ear deafness and dizziness, right ear, secondary to chronic secretory otitis media, thought to be due to virus infection. 4. After recovery under therapy which was con¬ tinued for two years, there was a sudden onset of partial inner-ear deafness, right ear, associated with an upper respiratory infection probably due to a virus.…”