Abstract:Although monolayer cells culture model has played great role in the study of biological phenomena and mechanisms about bystander effect, three dimensional (3D) culture model is believed to be much more appropriate in mimicking the in vivo physiological processes. In this study, human lung bronchial epithelial cells were firstly cultured in both 3D and monolayer model, then irradiated by X-rays and high-LET carbon ions, and finally co-cultured with normal lung fibroblast cell. The bystander γH2AXfoci were found… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.