Bursicon and the metabolism of tyrosine in the moulting cycle of Pieris larvae

Post, L. C.; Jong, B.J. de

doi:10.1016/0022-1910(73)90083-8

Cited by 16 publications

(1 citation statement)

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“…Using the blowfly bioassay, bursicon activity was subsequently reported in several other dipteran species including: Sarcophaga bullata (Cottrell, 1962b;Fraenkel andHsiao, 1962, 1965;Fogal and Fraenkel, Archives of Insect Biochemistry and Physiology June 2008 1969), Phormia regina (Fraenkel andHsiao, 1962, 1965), Lucilia spp (Cottrell, 1962b;Doy, 1972, 1973), and Drosophila melanogaster (Honegger et al, 2002;Dewey et al, 2004). Bursicon's presence has since been established in several other insect orders as well, including Orthoptera (Fraenkel and Hsiao, 1965;Honegger et al, 2002;Kostron et al, 1995Kostron et al, , 1996Kostron et al, , 1999Mills, 1965;Mills et al, 1965;Vincent, 1971Vincent, , 1972Srivastava and Hopkins, 1975), Hemiptera (Fraenkel and Hsiao, 1965), Coleoptera (Fraenkel and Hsiao, 1965;Kaltenhauser et al, 1995), and Lepidoptera (Fraenkel and Hsiao, 1965;Post, 1972;Post and De Jong, 1973;Reynolds, 1977;Reynolds et al, 1979;Taghert and Truman, 1982a,b;Truman, 1973).…”

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confidence: 99%

Transcriptional expression of bursicon and novel bursicon‐regulated genes in the house fly Musca domestica

Wang

Song

2008

Arch Insect Biochem Physiol

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Bursicon is a neuropeptide that regulates cuticle sclerotization (hardening and tanning) via a G protein-coupled receptor. It consists of two subunits, an alpha and a beta. In the present study, we investigated the transcriptional expression and in situ localization of bursicon α and β in the central nerve system of the house fly Musca domestica. Most importantly, we identified two novel bursicon-regulated genes using recombinant bursicon (rbursicon) heterodimer in a neck-ligated house fly assay. RT-PCR analysis revealed that both bursicon α and β subunits were present in the central nerve system of larval and pupal stages, reached the maximal level in pharate adults, and declined sharply after adult emergence, suggesting the release of the hormone upon adult emergence. In situ localization of bursicon transcripts showed that both bursicon α and β transcripts were expressed in a set of neurosecretory cells (NSCs) in the thoracic-abdominal ganglia of M. domestica. Two Drosophila melanogaster homologous genes, designated CG7985hh and CG30287hh, were up-regulated by rbursicon in a time-dependent manner and verified by real-time PCR, implying their involvement in the cuticle tanning process. Arch. Insect

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