Burden and risk factors of ambulatory or hospitalized CAP: A population based cohort study

Abstract

CAP constitutes a major burden in terms of incidence, morbidity and all-cause mortality in hospitalized and ambulatory patients. Interventions to raise awareness for disease impact also in ambulatory patients with risk factors are warranted.

Das neue Verständnis pulmonaler Infektionen

“…Die Sterblichkeit steigt drastisch bei älteren Patienten und vorliegenden Komorbiditäten. Insbesondere für chronische Herzinsuffizienz, Diabetes mellitus und Demenzerkrankungen konnte in verschiedenen Arbeiten eine erhöhte 1-Jahres-Mortalität gezeigt werden [15,33]. Das Spektrum der bakteriellen Infektionserreger einer CAP hat sich in den vergangenen Jahren nicht grundlegend geändert.…”

Antimicrobial resistance of clinical Streptococcus pneumoniae isolates in Russia: the results of multicenter epidemiological study «PEHASus 2014–2017»

“…Streptococcus pneumoniae является распространенным возбудителем инфекционных заболеваний у человека, вызывающим широкий круг различных клинических форм -от легких, склонных к спонтанному разрешению (острый отит, синусит, обострение хронического бронхита), до более тяжелых и крайне тяжелых жизнеугрожающих (пневмония, сепсис, менингит) [1][2][3]. Важнейшую роль в лечении пневмококковых инфекций играет выбор адекватной антимикробной терапии, которая в большинстве случаев носит эмпирический характер.…”

Community-Acquired Pneumonia in Adults

“…Current figures from health services research in Germany, based on data from the legally mandated health-insurance carriers, reveal an incidence of 9.7 cases per 1000 person-years, corresponding to more than 660 000 patients per year. Both the incidence and the mortality of CAP are ageand comorbidity-dependent (2,3). 46.5% of patients with CAP, and more than half of those aged 60 or above, are admitted to hospital for treatment (2).…”

“…Both the incidence and the mortality of CAP are ageand comorbidity-dependent (2,3). 46.5% of patients with CAP, and more than half of those aged 60 or above, are admitted to hospital for treatment (2). Hospitalized patients with CAP have a high in-hospital mortality of circa 13% (4).…”

“…Acute respiratory insufficiency and acute extrapulmonary organ dysfunction due to sepsis or comorbidities are the most important early prognostic parameters (6)(7)(8). Even after discharge from the hospital, there is still a high mortality related to comorbidities, particularly in elderly patients: according to a recent German study, in a group of patients whose median age was over 80, most of whom had chronic neurological or cardiac disease, the post-discharge mortality within 30 days of hospitalization was 4.7% (2,9). These figures have led to major conceptual changes in the characterization and treatment of CAP.…”