Bupropion increases cerebral activation in auditory affective processing: A randomized controlled fMRI study

Hama, Tomoko; Koeda, Michihiko; Ikeda, Yumiko; Tateno, Amane; Kawara, Tokuhiro; Suzuki, Hidenori; Okubo, Yoshiro

doi:10.1016/j.neulet.2021.135716

Cited by 5 publications

(3 citation statements)

References 52 publications

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“…Interestingly, the GM volume in the left insula was also significantly associated with emotional exhaustion. The insula is known to be involved in olfaction, gustation, somatosensory, and in the processing of negative emotions [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] . The left insula, which was specifically analyzed in this paper, is known to play an essential role in executive set-switching and language attainment [49] , [50] , which is crucial in complex medical situations.…”

Section: Discussionmentioning

confidence: 99%

Structural brain correlates of burnout severity in medical professionals: A voxel-based morphometric study

Abe

Tei

Takahashi

et al. 2022

Neuroscience Letters

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Section: Discussionmentioning

confidence: 99%

Structural brain correlates of burnout severity in medical professionals: A voxel-based morphometric study

Abe

Tei

Takahashi

et al. 2022

Neuroscience Letters

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“…However, we identified one cluster of regional hyperactivity during resting-state fMRI in the right superior temporal gyrus (rSTG) in SA. This brain region is implicated in emotion perception (Chen et al, 2021; Robins et al, 2009), spatial processing (Gharabaghi et al, 2006; Shah-Basak et al, 2018), and prediction of goal-directed movements of objects (Schultz et al, 2004) in healthy subjects, and its activity can be modulated by the antidepressant bupropion (Hama et al, 2021). In line with the evidence pinpointing this region as a hub for goal prediction, a magnetoencephalography study highlighted the possible role of the rSTG in sustaining working memory activity (Park et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Whole-brain structural and functional neuroimaging of individuals who attempted suicide and people who did not: a systematic review, exploratory coordinate-based meta-analysis and seed-based connectivity study

Meda

Miola

Cattarinussi

et al. 2022

Preprint

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IntroductionSuicide is the cause of death of approximately 800’000 people a year. Despite the relevance of this behaviour, risk assessment tools rely on clinician experience and subjective ratings.MethodsGiven that previous suicide attempts are the single strongest predictors of future attempts, we designed a systematic review and coordinate-based meta-analysis to evince if any neuroimaging features can help distinguish individuals who attempted suicide from subjects who did not. Out of 5659 publications from PubMed, Scopus and Web of Science, we summarised 102 experiments and meta-analysed 23 of them.ResultsA cluster in the right Superior Temporal Gyrus, a region implicated in emotional processing, might be functionally hyperactive in individuals who attempted suicide. Furthermore, we used JuSpace and the Human Brain Connectome dataset to show that this cluster is enriched in 5-HT1Aheteroreceptors, and its connectivity with the left central operculum is significantly correlated with loneliness scores.ConclusionsThis evidence provides a putative neural substrate for suicidal thought-to-attempt transition as hypothesised by Joiner’s Interpersonal Theory of Suicide. Heterogeneity in the analytical techniques and weak or absent power analysis of the studies included in this review currently limit the applicability of the findings, the replication of which should be prioritised.

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“…Individuals with unipolar depression display activity that is different from never-depressed individuals across a variety of networks subserving cognitive and emotional information processing in response to emotional stimuli (see Jaworska et al, 2015 for a review). Bupropion, an antidepressant, increases reactivity to happy voices in emotion circuits (e.g., superior temporal gyrus, superior and medial frontal gyrus, and insula) compared to the placebo ( Hama et al, 2021 ), despite no change in behavioral performance on vocal emotion judgments. This evidence encourages us to consider the phenomena of compromised affect perception in people with hearing problems within a broader framework.…”

Section: Affective Science Pertains To Audiologymentioning

confidence: 99%

Linking Affective and Hearing Sciences—Affective Audiology

Zhang,

Siegle

2023

Trends in Hearing

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A growing number of health-related sciences, including audiology, have increasingly recognized the importance of affective phenomena. However, in audiology, affective phenomena are mostly studied as a consequence of hearing status. This review first addresses anatomical and functional bidirectional connections between auditory and affective systems that support a reciprocal affect-hearing relationship. We then postulate, by focusing on four practical examples (hearing public campaigns, hearing intervention uptake, thorough hearing evaluation, and tinnitus), that some important challenges in audiology are likely affect-related and that potential solutions could be developed by inspiration from affective science advances. We continue by introducing useful resources from affective science that could help audiology professionals learn about the wide range of affective constructs and integrate them into hearing research and clinical practice in structured and applicable ways. Six important considerations for good quality affective audiology research are summarized. We conclude that it is worthwhile and feasible to explore the explanatory power of emotions, feelings, motivations, attitudes, moods, and other affective processes in depth when trying to understand and predict how people with hearing difficulties perceive, react, and adapt to their environment.

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Bupropion increases cerebral activation in auditory affective processing: A randomized controlled fMRI study

Cited by 5 publications

References 52 publications

Structural brain correlates of burnout severity in medical professionals: A voxel-based morphometric study

Structural brain correlates of burnout severity in medical professionals: A voxel-based morphometric study

Whole-brain structural and functional neuroimaging of individuals who attempted suicide and people who did not: a systematic review, exploratory coordinate-based meta-analysis and seed-based connectivity study

Linking Affective and Hearing Sciences—Affective Audiology

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