Bupivacaine versus lidocaine for third molar surgery: A double-blind, randomized, crossover study

Bouloux, Gary F.; Punnia‐Moorthy, A.

doi:10.1016/s0278-2391(99)90063-0

Cited by 55 publications

(43 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nine patients didn't need any analgesic tablets postoperatively and for three days after operation (5 subjects in bupivacaine group and 4 subjects in ropivacaine group); mean number of analgesic tablets consumed over 3 days was nearly equal for two groups. This study showed that ropivacaine did not differ from bupivacaine with respect to postoperative rescue analgesic requirement as reported by other authors [35,[42][43][44][45] who found that the increased duration of analgesia with long acting anaesthetics reduces the analgesic consumption after third molar surgery. Interestingly, a study of patients undergoing lower limb surgery who received ropivacaine hydrochloride for operative anaesthesia reported no use of supplemental analgesia in the first 24 hours after surgery by 37% of the patients.…”

Section: Discussionsupporting

confidence: 86%

Ropivacaine versus Bupivacaine in Postoperative Pain Control

Mansour¹

2012

J Biotechnol Biomaterial

View full text Add to dashboard Cite

Objective: The aim of this study was to compare between 2 types of long acting anesthetics: bupivacaine 0.5% and ropivacaine 0.75%, in terms of their duration of anesthesia, duration of analgesia and their effect in controlling postoperative pain after surgical removal of impacted lower third molars. Material and Methods:This study was conducted on fifty subjects referred to the Oral Surgery Department, Faculty of Dentistry, Mansoura University, for surgical removal of impacted lower third molar. Subjects were randomly assigned prior to surgery into 2 nerve block injections; the first group (group A) for an inferior alveolar nerve block (IANB) using bupivacaine and the second group (group B) for an IANB using ropivacaine. In each group, the patient's age, sex, type of impaction, severity of impaction was recorded. Time from the start of surgery till removal of impacted molar was taken as duration of surgery. Patients were instructed not to take any analgesics until numbness of lip and tongue receded.The time from onset of anaesthesia to when numbness of the lip and tongue receded as assessed by pricking is taken as the duration of anaesthesia. The time from the start of numbness to when the subject first requested a dose of oral analgesic (NSAID) was taken as duration of analgesia. Pain was assessed preoperatively and postoperatively, then patients instructed to record the extent of their pain at 3, 6, 9, and 12 hours on the day of surgery (D1), on the second (D2) and third days (D3) postoperatively. Post-operative analgesic consumption, inability to sleep because of pain, degree of overall satisfaction with the anaesthetic efficacy and postoperative pain management were considered. Results:The median duration of anaesthesia for the 7.5 mg/ml concentration of ropivacaine was approximately 6 hours, and for bupivacaine 5 mg/ml was approximately 7 hours. Bupivacaine can provide analgesia for 10.3 hours while ropivacaine can provide analgesia during the first 9.6 hours which is the period of maximum pain after third molar surgery. Conclusion:As regards a comparison of the study drugs with respect to post-operative pain experience, analgesic need and consumption, bupivacaine and ropivacaine appear to have equivalent efficacy.

show abstract

Section: Discussionsupporting

confidence: 86%

Ropivacaine versus Bupivacaine in Postoperative Pain Control

Mansour¹

2012

J Biotechnol Biomaterial

View full text Add to dashboard Cite

show abstract

“…Many studies reported that the combination of lidocaine hydrochloride with long acting local anesthetic will increase the duration of action and decrease patient discomfort [18]. Bupivacaine hydrochloride along with lidocaine hydrochloride is widely used for ophthalmic surgery as it has long duration of action [19] and there was no significant difference in cardiovascular response between the two groups [20]. Only few studies were conducted to compare the efficacy of carbonated bupivacaine with adrenaline with that of bupivacaine hydrochloride with adrenaline for surgical removal of impacted tooth.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Study Between Bupivacaine with Adrenaline and Carbonated Bupivacaine with Adrenaline for Surgical Removal of Impacted Mandibular Third Molar

Shyamala¹,

Ramesh²,

Yuvaraj³

et al. 2015

J. Maxillofac. Oral Surg.

View full text Add to dashboard Cite

Objectives To compare the effectiveness of bupivacaine with adrenaline with that of carbonated bupivacaine with adrenaline on pain, onset of anesthesia and duration of anesthesia following surgical removal of impacted mandibular third molar. Study design All the patients who underwent surgical removal of impacted mandibular third molar and who fulfilled our inclusion and exclusion criteria from 1st June 2013 to 30th June 2014 were included in our study. Patients who were diagnosed as having impacted mandibular third molar were randomly allocated to two groups namely group A (bupivacaine with adrenaline), group B (carbonated bupivacaine with adrenaline). Pain during deposition of local anesthetic, onset of anesthesia and duration of anesthesia were compared between the two groups. The collected data were subjected to statistical analysis by Chi Square test, Mann-Whitney U test. Results and conclusion The efficacy of carbonated bupivacaine with adrenaline is more compared with bupivacaine with adrenaline in decreasing pain on deposition of local anesthetic solution and in rapid onset of anesthesia. The duration of anesthesia for carbonated bupivacaine with adrenaline and bupivacaine with adrenaline had no significant difference. The use of carbonated bupivacaine with adrenaline will reduce the patient discomfort both intraoperatively and post-operatively.

show abstract

“…[12] Pain after third molar surgery can be of varying intensity and has been found to correlate with the duration of the procedure and the amount of surgical trauma. [13] The maximum postoperative pain is usually experienced during the first 6-8 hours so the use of bupivacaine improves postoperative comfort and reduces the need for strong analgesics.…”

Section: World Journal Of Pharmaceutical Researchmentioning

confidence: 99%