Bupivacaine, 0.125 Per Cent, in Obstetric Epidural Analgesia

Bleyaert, Achiel L.; Soetens, M.; Vaes, L.; Steenberge, A L Van; Donck, A. Van Der

doi:10.1097/00000542-197911000-00013

Cited by 45 publications

(7 citation statements)

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“…Extradural analgesia for labour frequently comprises local anaesthetics in small concentrations (0.125% bupivacaine, or less) [1], with or without adrenaline and highly lipid-soluble opioids such as fentanyl [2] or sufentanil [3]. Group B: bupivacaine 12.5 mg + adrenaline 25 ug + sufentanil 10 ug + clonidine 30 )ig.…”

Section: Methodsmentioning

confidence: 99%

Clonidine Combined With Sufentanil and Bupivacaine With Adrenaline for Obstetric Analgesia

Polain

Kock

Scholtès

et al. 1993

British Journal of Anaesthesia

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Clonidine produces analgesia via a non-opioid mechanism and it may be used as an interesting adjuvant to local anaesthetics and opioids in obstetric analgesia. To examine the effects of the addition of clonidine to bolus injections of bupivacaine, adrenaline and sufentanil, we enrolled 50 women receiving extradural analgesia for vaginal delivery into a double-blind study. They were allocated randomly to two groups: group A received a 10-ml extradural solution of bupivacaine 12.5 mg combined with adrenaline 25 micrograms and sufentanil 10 micrograms; group B received the same solution with clonidine 30 micrograms. Each patient was allowed two subsequent injections of the chosen solution. Subsequently, if still in the first stage of labour, analgesia was augmented with additional 10-ml injections of bupivacaine 12.5 mg with adrenaline 25 micrograms, without sufentanil or clonidine. The latter solution was used for perineal analgesia in group A; clonidine 30 micrograms was added in group B. During the first and second stages of labour, there was no difference between the two groups in duration of analgesia after the first injection (142 min in group A; 127 min in group B), number of injections (1.8 in group A; 1.9 in group B) and the total bupivacaine requirements (33.9 mg in group A; 34 mg in group B). The quality of analgesia was evaluated as very good in both groups (23/25 in group A; 24/25 in group B). The degree of motor block or the frequency of other side effects were not enhanced by clonidine.(ABSTRACT TRUNCATED AT 250 WORDS)

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Section: Methodsmentioning

confidence: 99%

Clonidine Combined With Sufentanil and Bupivacaine With Adrenaline for Obstetric Analgesia

Polain

Kock

Scholtès

et al. 1993

British Journal of Anaesthesia

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“…Bupivacaine in the concentration of 0.125% were used by Bleyert 68 , Kahn et al, 8,9 Guisasola. 10 They observed there was significant avoidance of motor blockade.…”

Section: Combined Spinal Epidural Techniquementioning

confidence: 99%

“…Unpleasant subjective awareness of numbness and paralysis in mother. 8 Most workers have commenced epidural analgesia when cervical dilatation was 3 cm or more. Since the active phase of first stage of labour is between 4cm till full cervical dilatation, in our study the labour analgesia was instituted with cervical dilatation between 3-5 cm, in view of making the technique convenient and comfortable for both patient and anaesthetist and avoid risk of injection of the drug at the time of painful uterine contractions.…”

Section: Commencing Of Epidural Analgesiamentioning

confidence: 99%

COMPARATIVE CLINICAL STUDY BETWEEN EPIDURAL AND COMBINED SPINAL EPIDURAL ANALGESIA ON LABOUR WITH 0.125% BUPIVACAINE AND 20μG FENTANYL

C¹,

Sreeraghu²,

Marwah³

et al. 2014

jemds

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“…Zur Inzidenz bei Epiduralanästhesien in der Geburtshilfe werden in der Literatur Zahlen von 0-36,2 pro 10.000 Blockaden angegeben [1,4,9,11,17,18,22,30,31,34,35]. Daneben kommen neurologische Ausfälle auch bei Geburten ohne Anästhesie vor.…”

Section: Diskussionunclassified

Neurologische postpartale Komplikationen nach geburtshilflicher Periduralanalgesie

et al. 2001

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Regional analgesia provides effective pain relief during delivery. Postpartal neurological deficits may be due to pressure of the fetal head on nerve structures at the pelvic rim or may be a complication of epidural analgesia. Nerve injuries due to spontaneous delivery and instrumental delivery are much more common than neurological deficits from epidural analgesia such as epidural hematoma or epidural abscess. The pattern of nerve damage is usually unilateral and non segmental. This case report describes the differential diagnosis of neurological deficit after spontaneous delivery under epidural analgesia and a discussion of the recent literature. Finally recommendations for the treatment of neurological deficits after delivery under epidural analgesia are presented.

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Bupivacaine, 0.125 Per Cent, in Obstetric Epidural Analgesia

Cited by 45 publications

References 0 publications

Clonidine Combined With Sufentanil and Bupivacaine With Adrenaline for Obstetric Analgesia

Clonidine Combined With Sufentanil and Bupivacaine With Adrenaline for Obstetric Analgesia

COMPARATIVE CLINICAL STUDY BETWEEN EPIDURAL AND COMBINED SPINAL EPIDURAL ANALGESIA ON LABOUR WITH 0.125% BUPIVACAINE AND 20μG FENTANYL

Neurologische postpartale Komplikationen nach geburtshilflicher Periduralanalgesie

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