Bullous Scabies

Increased risk of pemphigoid following scabies: a population‐based matched‐cohort study

“…One such atypical manifestation most common among the elderly are bullous lesions known as bullous pemphigoid‐like eruptions . The first case was described by Bean in 1974 with approximately 25 cases having been reported in the literature since that time . Although these eruptions are often considered a manifestation of scabies, the clinical, histological and immunological findings of this condition are identical to pemphigoid leading some researchers to debate that these blisters are actually features of bullous pemphigoid triggered by the parasite…”

A case of crusted scabies with a bullous pemphigoid‐like eruption and nail involvement

“…Light microscopy and direct immunofluorescence of a blister taken from our patient revealed a subepidermal bulla and IgG and C3 deposition on the dermoepidermal junction, these results were consistent with bullous pemphigoid. There are 13 previously reported cases, 3,[7][8][9][10][11][12][13][14][15][16] in eight of the 11 cases in which direct immunofluorescent study was performed, the results were positive. 9,11,12,[14][15][16] Therefore, light microscopy and direct immunofluorescent study are not sufficient to distinguish between true bullous pemphigoid and scabies with bullous lesions.…”

Bullous Scabies

“…Bullous lesions are rare in scabies [7,8], A few cases have been reported in which scabies mimicked bullous pemphigoid and in which light microscopy and even direct immunofluorescence were consistent with bullous pemphi goid. By indirect immunofluorescence, however, no auto antibodies could be found [5,6], In our patient direct immunofluorescence did not demonstrate immunoglobulins at the dermoepidermal junction, apart from nonspecific gran ular C3 deposits which are not uncommon in scabies 19 -1 1 1 just as granular deposits of IgM and IgG at the dermoepidcrmal junction and in perivascular locations in sca bies (9)(10)(11).…”