Bullous pemphigoid in a young male after COVID‐19 mRNA vaccine: a report and brief literature review

Abstract

question about a potential role of SARS-CoV-2 in the onset of DRESS. 4,9 A recent study showed that MPE observed in these COVID-19 patients could be favoured by the systemic cytokine storm promoting activation of monocytes/macrophages and eosinophils chemokines and cytotoxic CD8 + T cells. 10 Our study reinforces this hypothesis that SARS-CoV-2 infection could trigger DH by a particular pathophysiological mechanism that could involve eosinophils.

Influence of Covid‐19 vaccination on immune‐mediated skin diseases

“…We also identified more than 26 cases of vaccination‐related BP in the literature. 3 , 4 Other newly induced skin diseases in our patients were plaque psoriasis (patient 8) and chilblain‐like/gloves and socks‐like skin lesions (PPGSS, patient 10, Fig. 1i ).…”

Bullous pemphigoid after inactivated COVID ‐19 vaccination: Case report

“…To date, just about 20 new cases of BP related to the SARS‐CoV‐2 mRNA‐based vaccines produced by Pfizer and Moderna have been reported. 4 To our knowledge, the cases described here represent the first report of BP after administering inactivated COVID‐19 vaccine in China. A few cases of BP have been reported with other vaccines, including for swine flu and rabies vaccines, indicating that vaccination can lead basement membrane structure destruction.…”

Autoimmune mucocutaneous blistering diseases after SARS-Cov-2 vaccination: A Case report of Pemphigus Vulgaris and a literature review

“…A total of 195 articles was retrieved and after the screening, 20 articles were finally included for the review. A total of 35 AIBDs cases (including our case) were found, as shown in Table 1 [7] , [8] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] . The sub-epithelial diseases were the most frequent, accounting for 28 cases (80.0%), specifically 26 cases of BP (74.3%) and 2 case of LABD (5.7%).…”