Bullous and Pruritic Variant of Disseminated Superficial Actinic Porokeratosis: Successful Treatment with Grenz Rays

Abstract

We describe a case of intensively pruritic and partially bullous disseminated superficial actinic prorokeratosis, with acute flare-ups. Histopathological examination showed the characteristic cornoid lamella and subepidermal blister formation in one biopsy. Grenz ray treatment resulted in a marked regression of the skin lesions and pruritus.

Successful Use of Grenz Rays for Disseminated Superficial Actinic Porokeratosis: Report of 8 Cases

“…DSAP lesions are reported to have the potential of transformation into squamous cell carcinoma, Bowen's disease, or basal cell carcinoma [2] and usually cause cosmetic disturbances, therefore treatment is indicated. Various pharmacological and physical treatment options exist, but to our knowledge there is only 1 case report of successful porokeratosis treatment with grenz rays [3] . We present 8 cases of DSAP, successfully treated with radiotherapy (RTx) at the University Hospital Zurich.…”

Follicular involvement in porokeratosis

“…In addition to this follicular variant, other clinical presentations of DSAP have also been described, such as bullous and pruritic variant 9 and a hyperkeratotic subtype 10 …”

Eruptive pruritic papular porokeratosis: A pruritic variant of porokeratosis

“…Our review of the published work disclosed that four additional cases of pruritic porokeratosis were reported later ( Table 1). [2][3][4][5] Of these, three exhibited clinical features similar to those described by Kanzaki et al Only the patient reported by 1tork and Kodetová 3 had no pre-existing lesions and no tendency for spontaneous resolution in the course of 16-month follow up; this patient manifested peripheral eosinophilia.…”