BulkLMM: Real-time genome scans for multiple quantitative traits using linear mixed models
Zifan Yu,
Gregory Farage,
Robert W. Williams
et al.
Abstract:Genetic studies often collect data using high-throughput phenotyping. That has led to the need for fast genomewide scans for large number of traits using linear mixed models (LMMs). Computing the scans one by one on each trait is time consuming. We have developed new algorithms for performing genome scans on a large number of quantitative traits using LMMs, BulkLMM, that speeds up the computation by orders of magnitude compared to one trait at a time scans. On a mouse BXD Liver Proteome data with more than 35,… Show more
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