Bulbar Ligneous Conjunctivitis after Pterygium Removal in an Elderly Man

Prenatal diagnosis in a family with severe type I plasminogen deficiency, ligneous conjunctivitis and congenital hydrocephalus

“…Most affected children are healthy at birth and develop ligneous conjunctivitis during the first weeks or months of life. It has been suggested that minor trauma or infection of the conjunctival epithelium may initiate the development of this disorder (Holland et al, 1989;Weinstock and Kielar, 1975). Histological examination of pseudo-membranes from affected eyes or mucosa tissue from the genital tract exhibits a disrupted epithelium which is replaced by a massive deposition of fibrin and amorphous hyalin-like eosinophilic material and accompanied by an inflammatory cellular infiltration.…”

Long-term efficacy of surgical removal of pseudomembranes in a child with ligneous conjunctivitis treated with plasminogen eyedrops

“…Ligneous conjunctivitis (LC) is arare chronic membranous conjunctivitis with typical woody induration of the conjunctivaltissue.Recently,LChas been associatedwith type 1plasminogen deficiency(3), involving several mucosalareas: femalegenital tract,t racheobronchial tract and mouth.H ydrocephalus (6)(7)(8)(9) and Dandy Walker malformation (10)havebeen reportedinassociation with LC and plasminogend eficiency. In some cases LC seemst ob et riggered by mucopurulentalc onjunctivitiso r oculars urgery (11)(12)(13)(14). Topicalt reatment with hyaluronidase (15), corticosteroid, heparin (16) and cyclosporine (17) wasemployedwithoutstableresults.…”

Lignöz Konjonktivit

“…Pterygium eksizyonu sonrası bulber konjonktivada lignöz konjonktivit gözlenen bir olguda histokimyasal çalışmalar ile lezyonda hyaluronidaza duyarlı mukopolisakkarit gösterilmiş ve topikal hyaluronidaz ile alfa kemotripsin kullanılarak 20 aylık remisyon sağlanmıştır (36). Fibrinolizin ve krioterapi de lignöz konjonktivit tedavisinde uygulanmış olup, membran formasyonunun geciktirildiği gösterilmiştir (37).…”