Bulbar conjunctival metastasis from mucoepidermoid carcinoma of parotid—a case report and review of literature

Yadav, Rajshri; Battoo, Azhar Jan; Mir, Abdul Wahid; Haji, Altaf Gowhar

doi:10.1186/s12957-016-1077-0

Cited by 9 publications

(5 citation statements)

References 4 publications

(4 reference statements)

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“…Rare cases of cutaneous metastasis of MEC originating from different sites, like the bronchi should be taken into account [3]. Yadav et al, reported a case of an exophytic lesion of the left bulbar conjunctiva following treatment for high grade mucoepidermoid cancer of ipsilateral parotid gland, 9 months back [15]. For this reason a careful evaluation of the patients to look for occult neoplasms in distant sites needs to be done.…”

Section: Discussionmentioning

confidence: 99%

“…For this reason a careful evaluation of the patients to look for occult neoplasms in distant sites needs to be done. It is recommended to perform blood chemistry profile, complete blood count together with diagnostic imaging like total body Positron Emission Tomography and Computed Tomography Scan and p63 immunostaining to differentiate cutaneous metastasis from primary MEC [10,15,16].…”

Section: Discussionmentioning

confidence: 99%

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Mucoepidermoid Carcinoma of the Eyelid: A Rare Presentation

Akhtar¹

2017

INID

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Mucoepidermoid Carcinoma of the Eyelid: A Rare Presentation

Akhtar¹

2017

INID

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“…Overt cytologic atypia or mitotic activity is absent and there are often prominent inflammatory cells in the background. 9 Yadav et al 10 have reported a case of metastatic MEC involving the bulbar conjunctiva from the parotid gland. No evidence of preexisting MEC was found in both cases on history and systemic workup.…”

Section: Discussionmentioning

confidence: 99%

Conjunctival Adenosquamous Carcinoma Lacks MAML2 Translocation: A Variant of Squamous Cell Carcinoma With Mucoepidermoid Differentiation and Aggressive Behavior?

et al. 2020

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Conjunctival adenosquamous carcinoma, also known as mucoepidermoid carcinoma (MEC), is a rare tumor that preferentially affects the perilimbal area of the conjunctiva with aggressive local invasion. Consisting of infiltrative proliferation of squamous cells and mucous cells, its morphologic features are reminiscent of the salivary gland-type MEC except for the absence of intermediate cells and frequent keratin production. We reported 2 cases of conjunctival adenosquamous carcinoma and, for the first time, studied the MAML2 translocation status of this rare entity. The 2 patients were women, aged 45 and 42 years, presenting with an erythematous lesion in the left lower palpebral conjunctiva and a pigmented nodule over the left nasal conjunctiva, respectively. One tumor recurred 6 months after the initial biopsy. Excision with lid reconstruction and postoperative radiotherapy was performed for margin involvement and perineural invasion. This patient was disease free at 3-year follow-up. The other patient was lost to follow-up after tumor excision. Fluorescence in situ hybridization and reverse transcription polymerase chain reaction failed to demonstrate MAML2 translocation and CRCT1-MAML2 transcripts in both tumors. The absence of this characteristic translocation and reappraisal of the cellular composition, morphologic features, and precursor lesion suggest that conjunctival MEC may represent a variant of conjunctival squamous cell carcinoma but not related to the salivary gland-type MEC.

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“…In 1945, Stewart and associates described the mucous secreting and epidermal cellular component of mucoepidermoid carcinoma, thus establishing it as a distinct pathological entity [7]. Bhasker in 1963 reported 2 cases and analyzed the criteria for their central origin, histology and pathogenesis [1].…”

Section: Introductionmentioning

confidence: 99%

Intraosseous mucoepidermoid carcinoma of the mandible – a rare case report

Sankireddy¹,

Kaushik²,

Vijaychander³

et al. 2015

RSBO

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Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The majority of these tumors arises in the parotid and minor salivary glands but may rarely develop intraosseously. Primary intraosseous mucoepidermoid carcinoma (PIOC) of the jaw bones is an extremely rare malignant salivary gland tumor. Very few cases have been reported in the literature to date. Case report: The current manuscript highlights clinical and radiographic features of a rare case of PIOC in a 32 year old Indian female patient. Conclusion: All the dental practitioners should be aware of the protean features of central MEC. These lesions should be included in the differential diagnosis of unilocular and multilocular radiolucent lesions of the jaws. An early and accurate diagnosis is important so that the neoplastic transformation must be identified and treated effectively.

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Bulbar conjunctival metastasis from mucoepidermoid carcinoma of parotid—a case report and review of literature

Cited by 9 publications

References 4 publications

Mucoepidermoid Carcinoma of the Eyelid: A Rare Presentation

Mucoepidermoid Carcinoma of the Eyelid: A Rare Presentation

Conjunctival Adenosquamous Carcinoma Lacks MAML2 Translocation: A Variant of Squamous Cell Carcinoma With Mucoepidermoid Differentiation and Aggressive Behavior?

Intraosseous mucoepidermoid carcinoma of the mandible – a rare case report

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