Building wireless implantable neural interfaces within weeks for neuroscientists

Bentler, C.

doi:10.1109/embc.2017.8037014

Cited by 4 publications

(2 citation statements)

References 11 publications

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“…A hybrid COTS–custom implantable wireless neuroprosthetic is presented in [ 76 ]. The application’s neuroprosthetic implantable device is custom designed and utilizes a COTS USRP B210 software defined radio (SDR) for telemetry.…”

Section: Essential Building Blocks Of Cots-enabled Iwmdsmentioning

confidence: 99%

Commercial Off-the-Shelf Components (COTS) in Realizing Miniature Implantable Wireless Medical Devices: A Review

Khan

Mugisha

Tsiamis

et al. 2022

Sensors

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Over the past decade, there has been exponential growth in the per capita rate of medical patients around the world, and this is significantly straining the resources of healthcare institutes. Therefore, the reliance on smart commercial off-the-shelf (COTS) implantable wireless medical devices (IWMDs) is increasing among healthcare institutions to provide routine medical services, such as monitoring patients’ physiological signals and the remote delivery of therapeutic drugs. These smart COTS IWMDs reduce the necessity of recurring visits of patients to healthcare institutions and also mitigate physical contact, which can minimize the possibility of any potential spread of contagious diseases. Furthermore, the devices provide patients with the benefit of recuperating in familiar surroundings. As such, low-cost, ubiquitous COTS IWMDs have engendered the proliferation of telemedicine in healthcare to provide routine medical services. In this paper, a review work on COTS IWMDs is presented at a macro level to discuss the history of IWMDs, different networked COTS IWMDs, health and safety regulations of COTS IWMDs and the importance of organized procurement. Furthermore, we discuss the basic building blocks of IWMDs and how COTS components can contribute to build these blocks over widely researched custom-built application-specific integrated circuits.

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Section: Essential Building Blocks Of Cots-enabled Iwmdsmentioning

confidence: 99%

Commercial Off-the-Shelf Components (COTS) in Realizing Miniature Implantable Wireless Medical Devices: A Review

Khan

Mugisha

Tsiamis

et al. 2022

Sensors

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“…While it is clearly the hope that every new tool can be successfully adopted, there are major challenges in transitioning neural recording devices from the initial research and development phase into the basic science laboratory. A universal challenge is providing a strong incentive for neuroscientists to use a specific type of device over alternative products [27]. This incentive could be based on favorable technical capabilities (e.g., structural dimensions, number or arrangement of electrodes), as well as less quantifiable but nonetheless important considerations such as availability and convenience [28].…”

Section: Introductionmentioning

confidence: 99%

Open source silicon microprobes for high throughput neural recording

Yang¹,

Lee²,

Villagracia³

et al. 2020

J. Neural Eng.

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Objective.-Microfabricated multielectrode arrays are widely used for high throughput recording of extracellular neural activity, which is transforming our understanding of brain function in health and disease. Currently there is a plethora of electrode-based tools being developed at higher education and research institutions. However, taking such tools from the initial research and development phase to widespread adoption by the neuroscience community is often hindered by several obstacles. The objective of this work is to describe the development, application, and open dissemination of silicon microprobes for recording neural activity in vivo.Approach.-We propose an open source dissemination platform as an alternative to commercialization. This framework promotes recording tools that are openly and inexpensively available to the community. The silicon microprobes are designed in house, but the fabrication and assembly processes are carried out by third party companies. This enables mass production, a key requirement for large-scale dissemination.Main results.-We demonstrate the operation of silicon microprobes containing up to 256 electrodes in conjunction with optical fibers for optogenetic manipulations or fiber photometry. These data provide new insights about the relationship between calcium activity and neural spiking activity. We also describe the current state of dissemination of these tools. A file repository of resources related to designing, using, and sharing these tools is maintained online.Significance.-This paper is likely to be a valuable resource for both current and prospective users, as well as developers of silicon microprobes. Based on their extensive usage by a number of labs including ours, these tools present a promising alternative to other types of electrode-based technologies aimed at high throughput recording in head-fixed animals. This work also demonstrates the importance of validating fiber photometry measurements with simultaneous electrophysiological recordings.

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Recent advances in wireless epicortical and intracortical neuronal recording systems

Liang

Yuan

et al. 2022

Sci. China Inf. Sci.

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Building wireless implantable neural interfaces within weeks for neuroscientists

Cited by 4 publications

References 11 publications

Commercial Off-the-Shelf Components (COTS) in Realizing Miniature Implantable Wireless Medical Devices: A Review

Commercial Off-the-Shelf Components (COTS) in Realizing Miniature Implantable Wireless Medical Devices: A Review

Open source silicon microprobes for high throughput neural recording

Recent advances in wireless epicortical and intracortical neuronal recording systems

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