Building the interaction interfaces: host responses upon infection with microorganisms

Yamazaki, Akihiro; Hayashi, Makoto

doi:10.1016/j.pbi.2014.12.003

Cited by 16 publications

(8 citation statements)

References 75 publications

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“…As in many eukaryotic polarized systems, where localized exocytosis targets PI(4,5)P 2 -rich membrane domains, accumulation of this phosphoinositide was also shown to occur on perimicrobial membranes during pathogenic infections (Qin et al, 2020) and during AM symbiosis, where PI(4,5)P 2 specifically accumulated at the tips of intracellular linear hyphae (Ivanov & Harrison, 2019). Taken together, our data strongly support the hypothesis that IT polarity requires few specific factors like RPG but predominantly relies on a highly conserved mechanism as suggested earlier (Gage, 2004; Yamazaki & Hayashi, 2015). While the secretion domain in curled root hairs comprises the entire IC (Fournier et al, 2015), the loss of highly restricted focal polarization results in the formation of enlarged ITs (Figure 1B-D).…”

Section: Discussionsupporting

confidence: 91%

RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections

Lace

Perez

et al. 2022

Preprint

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Host-controlled intracellular accommodation of nitrogen-fixing bacteria is essential for the establishment of a functional Root Nodule Symbiosis (RNS). In many host plants, this occurs via transcellular tubular-structures (infection threads - ITs) that extend across cell layers via polar tip-growth. Comparative phylogenomic studies have identified RPG (RHIZOBIUM-DIRECTED POLAR GROWTH) among the critical genetic determinants for bacterial infection. In Medicago truncatula, RPG is required for effective IT progression within root hairs but the cellular and molecular function of the encoded protein remain elusive. Here, we show that RPG resides in the protein complex formed by the core endosymbiotic components VAPYRIN (VPY) and LUMPY INFECTION (LIN) required for IT polar growth, co-localizes with both VPY and LIN in IT tip- and perinuclear-associated puncta of M. truncatula root hairs undergoing infection and is necessary for VPY recruitment to puncta. Fluorescence Lifetime Imaging Microscopy (FLIM) of phosphoinositide species during bacterial infection revealed that functional RPG is required to sustain strong membrane polarization at the advancing tip of the IT. In addition, loss of RPG functionality alters the cytoskeleton-mediated connectivity between the IT tip and the nucleus and affects polar secretion of the cell wall modifying enzyme NODULE PECTATE LYASE (NPL). Our results integrate RPG into a core host machinery required to support symbiont accommodation, suggesting that its occurrence in plant host genomes is essential to co-opt a multimeric protein module committed to endosymbiosis to sustain IT-mediated bacterial infection.

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Section: Discussionsupporting

confidence: 91%

RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections

Lace

Perez

et al. 2022

Preprint

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“…To survive in sub-optimal conditions, plants have evolved a repertoire of mechanisms to combat harmful external cues ( Boller and Felix, 2009 ; Yamazaki and Hayashi, 2015 ). Recognition of attempted infection or insect infestation leads to reprogramming of basic metabolism and production of deterring chemical compounds to prevent pathogens and pests from colonizing the host plant tissue.…”

Section: Introductionmentioning

confidence: 99%

Protein Phosphatase 2A in the Regulatory Network Underlying Biotic Stress Resistance in Plants

et al. 2016

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Biotic stress factors pose a major threat to plant health and can significantly deteriorate plant productivity by impairing the physiological functions of the plant. To combat the wide range of pathogens and insect herbivores, plants deploy converging signaling pathways, where counteracting activities of protein kinases and phosphatases form a basic mechanism for determining appropriate defensive measures. Recent studies have identified Protein Phosphatase 2A (PP2A) as a crucial component that controls pathogenesis responses in various plant species. Genetic, proteomic and metabolomic approaches have underscored the versatile nature of PP2A, which contributes to the regulation of receptor signaling, organellar signaling, gene expression, metabolic pathways, and cell death, all of which essentially impact plant immunity. Associated with this, various PP2A subunits mediate post-translational regulation of metabolic enzymes and signaling components. Here we provide an overview of protein kinase/phosphatase functions in plant immunity signaling, and position the multifaceted functions of PP2A in the tightly inter-connected regulatory network that controls the perception, signaling and responding to biotic stress agents in plants.

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“…The plant probiotic and plant growth and yield enhancing microbes have the ability to colonize the rhizosphere, rhizoplane and sometimes even the endorhizosphere of the plant's roots, phyllosphere, endosphere, spermosphere, and other possible micro-niches in the plant (Van Der Heijden et al 2008;Babalola 2010;Prasad et al 2015). The microbes associated with these microclimates around, on, and inside the plant roots and aerial organs exhibit very diverse and complex relationships well-regulated and orchestrated through specific low-molecular weight compounds, the signal molecules, which ensure proper monitoring of the surroundings, cell-cell communication, and recognition of the compatible partners (Schlaeppi and Bulgarelli 2015;Yamazaki and Hayashi 2015;Igiehon and Babalola 2018).…”

Section: Plant-microbe Interaction Systemmentioning

confidence: 99%

“…The active mechanism involves the secretion of two fundamental groups of compounds, i.e., diffusible and secretory low-molecular weight compounds such as antibiotics, bacteriocins, small lipoproteins, lytic enzymes (proteases, chitinases), volatile organic compounds, and metal-chelating siderophores, which offer cidal/killing (antibiosis) effect or pose competition to the phytopathogens, thereby curbing their attack (Tikhonovich and Provorov 2011). The passive mechanism of plant probiotic action involves competition and occupancy of the receptor ligand sites on the surfaces of the plant tissues and organs and formation of homogenous or heterogeneous biofilms on the exterior as well as internal plant tissues (Yamazaki and Hayashi 2015). Furthermore, Panke-Buisse et al ( 2017) have observed regulation and induction of early flowering trait in model plant Arabidopsis thaliana to be governed through the cultivable microbiome teased out of the whole microbiome of the test plant.…”

Section: Beneficial Plant-microbe Interactionsmentioning

confidence: 99%

Plant-Microbe Interactions: Applications for Plant-Growth Promotion and In Situ Agri-waste Management

Kalia

Singh

2020

Plant Microbiome Paradigm

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The microbial genera, both cultivable and uncultivable, associated with the host plant inhabiting in or on different tissues or organ and the environment surrounding the plant body are unique and comprise the plant-associated microbiome (PAM). The PAM profile of the host plant gets altered in response to certain biotic and abiotic stresses and the anthropogenic interventions. Therefore, identification of key groups or genera of the microbes among the whole PAM is critical as these microbes, besides themselves, can modulate several other microbial communities, leading to considerable positive or negative changes in the community structure, abundance, and the overall microbial diversity. This manuscript explores the alterations in PAM particularly in response to the agri-management practices and its role in enhancing growth, vigor, and yield in host crop plants. Further, the precise role of a specific group of PAM, the soil organic matter decomposers, has been discussed with special reference to agri-waste generated by cereal crop cultivation. The practical applications of the PAM studies for improvement in the agricultural sustainability through optimization of the plant microbiome have also been discussed. IntroductionThe soil microbial communities and their role in ecosystem regulation including waste decomposition, nutrient cycling, transformation, and availability are crucial for crop production (Hartman et al. 2018). These soil-dwelling organisms including the microbes and higher organisms do not exist in isolation rather are interwoven in

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Building the interaction interfaces: host responses upon infection with microorganisms

Cited by 16 publications

References 75 publications

RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections

RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections

Protein Phosphatase 2A in the Regulatory Network Underlying Biotic Stress Resistance in Plants

Plant-Microbe Interactions: Applications for Plant-Growth Promotion and In Situ Agri-waste Management

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