“…Implementation science approaches will be needed to make such long-term studies affordable and practical. 8 Second, treatment fatigue might have been seen in the trial by Lippman and colleagues, as both community mobilisation and control group communities saw a decline in retention rates over the 3-year study period. 3 Making it easier to obtain ART and maintain usage might require programmatic innovation, use of longacting injectable antiretroviral drugs, and supply chain improvements to avoid drug stockouts.…”