Buffer Optimization for Cynodon dactylon Proteome

Abstract

Purpose: To evaluate the treatment outcomes of chemoradiotherapy for patients with advanced esophageal cancer and estimate the prognostic factors. Materials and methods:Patients with advanced esophageal cancer, who were treated with chemoradiotherapy (CRT) between April 2003 and December 2010, were evaluated. Patients received concurrent chemoradiotherapy (cisplatin plus 5-fluorouracil and 61.2 Gy radiotherapy). Therapeutic response, overall survival time, and toxicity were examined and statistical evaluation was performed.Results: One hundred and fourteen patients were treated with CRT. Among them, 84 patients (77.2%) received the complete course of CRT. Eighteen patients (15.8%) had a complete response, 90 patients (78.9%) had a partial response and 6 patients (5.3%) exhibited progressive disease. The mean follow-up period was 14.6 months (range, 2-90 months). The median overall survival time was 13.0 months. The 2-year and 3-year overall survival rates were 38.1% and 19.2%, respectively. Severe hematological toxicities included Grade 3 leukopenia in 40 patients (35.1%). Treatment-related death was estimated to have occurred in 7 patients. Performance status and body weight loss were identified as significant prognostic factors. Conclusion:In our study, PS and body weight loss showed prognostic factors in CRT for advanced esophageal cancer.

Organic Acids Production by Zinc Solubilizing Bacterial Isolates

“…The samples were withdrawn at 5, 10 and 15 days intervals, centrifuged to remove the debris and cells. The supernatant was collected and filtered through 0.2µm poly vinylidenedifluoride (PVDF) syringe filters and estimated the different organic acids by HPLC (Model: Prominence, Shimadzu, Japan) technique (Tahir and Shakeel, 2013). The organic acids detected were identified by comparing their retention time and the peak areas of their chromatograms with the standard organic acids.…”