Budd-Chiari Syndrome Treated with Acylated Streptokinase-Plasminogen Complex

Thrombosis in paroxysmal nocturnal hemoglobinuria: sites, risks, outcome. An overview

“…The initial success is >80% with long‐term patency of 65%. While thrombolytic therapy is most helpful when initiated within 48–72 h, attempting this treatment may be worthwhile even in patients who have had symptoms for 2–3 weeks [6–9]. In contrast, the results of liver transplantation in PNH were not very good [10–12].…”

Temporal trends in mortality rates from visceral vein thrombosis in paroxysmal nocturnal haemoglobinuria: An optimistic view

“…However, there are still unresolved problems, especiallyshort-termpatencyofthe shunt due to intimal hyperplasia, whichc auses ar eduction of the shunt lumen thus favouring recurrence of portal hypertension and variceal bleeding (9). Earlyintervention with thrombolytic therapymay be warranted because hepatic venous outflowobstruction canbe relieved with totalr ecovery of the hepatic function (10)(11)(12). Thrombolysis seems to minimize the risk of death in PNH (1).…”

Budd-chiari syndrome in patients with hematological disease: A therapeutic challenge

“…While thrombolytic therapy is most helpful when initiated within 48 to 72 hours, attempting this treatment may be worthwhile even in patients who have had symptoms for 2 or 3 weeks. 12,13 Balloon angioplasty has also been used successfully in patients with a combination of hepatic vein and IVC occlusion. However, the patency Curative for protein C, S, and anti-thrombin III deficiencies.…”