1986
DOI: 10.1136/ard.45.5.435
|View full text |Cite
|
Sign up to set email alerts
|

Budd-Chiari syndrome as the major thrombotic complication of systemic lupus erythematosus with the lupus anticoagulant.

Abstract: SUMMARY A patient with systemic lupus erythematosus was first diagnosed after she had developed the Budd-Chiari syndrome. We believe that the Budd-Chiari syndrome was part of her tendency for thrombosis, induced by the presence of a lupus anticoagulant. The association between enhanced thrombosis and the lupus anticoagulant is discussed, and the need for prompt recognition and administration of anticoagulant therapy is emphasised.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
6
0
1

Year Published

1989
1989
2013
2013

Publication Types

Select...
6
4

Relationship

0
10

Authors

Journals

citations
Cited by 36 publications
(7 citation statements)
references
References 13 publications
0
6
0
1
Order By: Relevance
“…2 The thrombotic events in AP involve the hepatic circulation, most frequently as the BuddChiari syndrome. [6][7][8][9][10][11][12][13] There are three previous reports of APS and portal vein thrombosis [14][15][16] in which patients had severe symptoms associated with portal thrombosis, esophageal varices from portal hypertension, 14,15 or hepatic infarction, 16 whereas our patient had only nonspecific but common symptoms, such as abdominal pain and fever. Moreover, his portal thrombus disappeared spontaneously (Fig.…”
Section: Discussionmentioning
confidence: 47%
“…2 The thrombotic events in AP involve the hepatic circulation, most frequently as the BuddChiari syndrome. [6][7][8][9][10][11][12][13] There are three previous reports of APS and portal vein thrombosis [14][15][16] in which patients had severe symptoms associated with portal thrombosis, esophageal varices from portal hypertension, 14,15 or hepatic infarction, 16 whereas our patient had only nonspecific but common symptoms, such as abdominal pain and fever. Moreover, his portal thrombus disappeared spontaneously (Fig.…”
Section: Discussionmentioning
confidence: 47%
“…Seven reports of hepatic vein occlusion resulting in Budd-Chiari syndrome have been published. [21][22][23][24][25][26][27] The antibodies may also be of importance in the pathogenesis of other hepatic lesions, some of which have a vascular basis and involve smaller intrahepatic vessels. 28 In 1998 Perez-Ruiz et al suggested a possible role of the aPL in the pathogenesis of nodular regenerative hyperplasia of the liver (NRHL).…”
Section: Primary Antiphospholipid Antibody Syndromementioning
confidence: 99%
“…18 The association of this syndrome with lupus anticoagulant was reported in one patient in 1984 but the patient did not fulfill the required criteria proposed for the diagnosis of SLE. 19 Our patient satisfied the criteria proposed for the diagnosis of SLE; here the cause of hepatic vein thrombosis is the presence of lupus anticoagulant that interferes with the normal function of blood vessels causing vasculopathy and ultimately thrombosis.…”
Section: Discussionmentioning
confidence: 99%