Budd-Chiari syndrome after taking oral contraceptives.

Hepatic Lesions Caused by Anabolic and Contraceptive Steroids

“…4). Hemorrhagic infarcts [141], calcification 158,1641 and regenerative nodules [3,67] have been described. Some of the cases have had thrombosis of the portal vein and other intraabdominal veins [19,21,28,67,87,133].…”

Hormonal Steroid Contraceptives1 III

“…Thrombosis of the hepatic vein (Budd-Chiari syndrome) has been reported by Sterup andMosbech (1967), Chamberlain andWalter (1969) and by Hoyumpa et al (1971). Welin and Persson (1968) reported thrombosis of the coeliac artery, and Brennan.…”

Long-term effects on the liver

“…However, a somewhat similar syndrome of periportal vascular dilatation and jaundice has recently been described in patients on oral contraceptives by Poulsen and Winkler (1973), and it may be that the basis of the two lesions is the same. An entirely different way in which contraceptives cause vascular disease is seen when there is thrombosis of hepatic veins leading to the Budd-Chiari syndrome (Sterup and Mosbech, 1967).…”