Bubonic plague: Can the size of buboes be accurately and consistently measured with a digital calliper?
Josephine Bourner,
Ravaka Randriamparany,
Tsinjo Fehizoro Rasoanaivo
et al.
Abstract:Introduction: Conducting clinical research on treatments for emerging infectious diseases is often complicated by methodological challenges, such as the identification of appropriate outcome measures to assess treatment response and the lack of validated instruments available to measure patient outcomes. In bubonic plague, some studies have assessed bubo size as an indicator of treatment success, a measure widely assumed to be indicative of recovery. Evaluating this outcome however is challenging as there is n… Show more
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