Brusellozisli Sığırlarda Oksidatif Stres İndeksi ve Lipid Profilinin İncelenmesi

Merhan, Oğuz; Bozukluhan, Kadir; Kuru, Mushap; Büyük, Fatih; Özden, Özkan; Kükürt, Abdulsamed

doi:10.9775/kvfd.2017.18004

Cited by 4 publications

(3 citation statements)

References 17 publications

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“…Blood contains many antioxidants that act to neutralize ROS, or prevent the release of ions responsible for initiating lipid peroxidation [17]. Merhan et al [18] reported that in case of inflammation and hyperglycemia, antioxidant defense gets weakens and the increased reactive oxygen species leads to oxidative stress.…”

Section: Resultsmentioning

confidence: 99%

Oxidative Stress Status in Sera and Saliva of Type 2 Diabetic Iraqi Patients with and without Proliferative Diabetic Retinopathy

2019

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The present study aimed to look for the differences in the oxidative stress status in sera and saliva samples of type 2 diabetic Iraqi patients with and without proliferative diabetic retinopathy. As well as to look for the possibility whether this status can be measured in saliva as an alternative sample to that of serum, hence to achieve that total oxidant status, total antioxidant status and oxidative stress index were measured in both sera and saliva samples of two groups of patients with type 2 diabetes mellitus and the healthy individuals. Upon the comparison between patients without proliferative diabetic retinopathy and the control sample the results showed presence of a significant increase (p < 0.05) of total oxidant status and oxidative stress index in sera and saliva samples, while there was a significant decrease (p < 0.05) in total antioxidant status of sera and saliva samples. Meanwhile when the comparison was done between patients with proliferative diabetic retinopathy and those without proliferative diabetic retinopathy, a significant increase (p < 0.05) in both salivary total oxidant status and oxidative stress index was observed with a significant decrease (p < 0.05) in sera and salivary total antioxidant status were found in the proliferative diabetic retinopathy patients group.

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Section: Resultsmentioning

confidence: 99%

Oxidative Stress Status in Sera and Saliva of Type 2 Diabetic Iraqi Patients with and without Proliferative Diabetic Retinopathy

2019

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“…This form of damage is predominantly indirect and is instigated by the generation of ROS. The chemical species, H2O2 (hydrogen peroxide), OH (hydroxyl radical), and O2 (superoxide radical) have been reported in the literature [5]. Endogenous sources (such as mitochondria, peroxisomes, phagocytic cells, etc.)…”

Section: Introductionmentioning

confidence: 99%

Relation of MDA as Oxidative Stress Marker with Lipid Profile in a Diabetic Patient

M. Azeez,

K. AL-Hashemi,

F. R. Al-Auqbi

et al. 2023

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Type-2 diabetes mellitus (T2DM) is a disease accompanied by induced oxidative stress (OS) conditions. A reduction in antioxidant activity characterizes the OS conditions. Antioxidants protect cell components from the harmful effects of reactive oxygen species (ROS). The oxidation of the lipid components by ROS has the potential to generate malondialdehyde (MDA). The assessment of MDA (which is a byproduct of lipid peroxidation) may serve as a sign of oxidative damage. This can shed light on the impact of ROS on lipids. This study aims to elucidate the correlation between MDA oxidative stress biomarkers and lipids in individuals diagnosed with type-2 diabetes mellitus. The study comprises two case groups of 30 diabetic patients, 30 obese patients, and 30 healthy patients as the control group. The levels of MDA in the plasma specimens are measured. The serum glucose, serum lipid, and glycated haemoglobin (HbA1c) are evaluated for these groups. The results among patients with and without T2DM are analyzed with regard to age and BMI. The concentration of the MDA is [17.08 ± 1.989 (nmol/ml)] for diabetic patients, [16.08 ± 2.049 (nmol/ml)] for obese patients, and [12.12 ± 1.508 (nmol/ml)] for control patients. A statistically significant difference of p <0.0001 is observed in the elevated levels of MDA among T2DM patients. As compared to healthy control participants, there is no significant difference between T2DM and obese patients. It is concluded that the MDA can be utilized for observing the oxidative stress related to T2DM. The data indicate that utilising MDA could help predict the oxidative environment.

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“…by free radicals and reactive oxygen species are involved in the pathogenesis of many tissue-damaging diseases (Ergönül and Kontaş Aşkar, 2009;Erkılıç et al, 2017;Merhan et al, 2020;Ertaş and Kırmızıgül, 2021;Öner et al, 2022). Protein oxidation can be described as the covalent modi cation of proteins induced directly by reactive oxygen species such as OH˙, H 2 O 2 or indirectly by reaction with secondary products of oxidative stress (Polat, et al, 2012).…”

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confidence: 99%

Investigation of Aopp, Total Sulphydryl Group (T-sh), Seroplasmin Levels in Sheep Wi̇th Zoonotic Liver Parasitosis

OĞUZ,

KÖMÜROĞLU,

AYAN

et al. 2024

Preprint

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The aim of inthe present study was to investigate aopp, total sulfhydryl group (t-sh) and seroplasmin levels in zoonotic liver parasitosis in sheep. this study was carried out in Iğdır province. For this purpose, 75 sheep were grouped as healthy, Fasciola spp., Echinococcus spp., Dicrocoelium spp., Echinococcus spp. + Dicrocoelium spp. The levels of the specified parameters were measured in these groups. According to the results, AOPP level in the fasciolosis group was remarkably higher than all other groups (p < 0.05). The serum AOPP level in the E + D group was found to be significantly higher compared to the control and dicrocoelium spp. groups (p < 0.05). Echinococcus spp. group was s remarkably higher than the dicrocoelium spp. group (p < 0.05). The ceruloplasmin level in the control group was found to be significantly lower compared to the Echinococcosis, fasciolosis and dicrocoeliosis groups (p < 0.05). Total sulfhydryl level was found to be lower in the patient groups compared to the healthy group, but this value was not significant. According to these results, it can be said that cellular damage occurs in liver parasitism. These parameters are thought to be valuable in terms of prognosis in parasitic infections. It is also thought that oxidative cell damage occurs in the attack of zoonotic liver parasites in which the immune response decreases. It is thought that this study will serve as a guide for future research.

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Brusellozisli Sığırlarda Oksidatif Stres İndeksi ve Lipid Profilinin İncelenmesi

Cited by 4 publications

References 17 publications

Oxidative Stress Status in Sera and Saliva of Type 2 Diabetic Iraqi Patients with and without Proliferative Diabetic Retinopathy

Oxidative Stress Status in Sera and Saliva of Type 2 Diabetic Iraqi Patients with and without Proliferative Diabetic Retinopathy

Relation of MDA as Oxidative Stress Marker with Lipid Profile in a Diabetic Patient

Investigation of Aopp, Total Sulphydryl Group (T-sh), Seroplasmin Levels in Sheep Wi̇th Zoonotic Liver Parasitosis

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