Brunneroma – A Rare Tumour of the Duodenum

Sj, Varghese; Dhot, PS; Bhardwaj, T. R.; Paul, Paul; Hk, Kapoor

doi:10.1016/s0377-1237(17)30649-4

Cited by 1 publication

(2 citation statements)

References 3 publications

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“… 1 , 4 An isolated mass containing proliferative BG is called a BG hamartoma or adenoma (these terms are often used interchangeably), 1 , 5 or a Brunneroma. 6 , 7 Some authors favor the term hamartoma/adenoma over hyperplasia for lesions with a diameter greater than 5 mm, or for those including interspersed fibrous connective tissue, adipose or lymphoid tissue. 1 , 5 The distinction between hamartoma and adenoma in these cases may be academic, as both are benign proliferative lesions.…”

Section: Discussionmentioning

confidence: 99%

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Brunner’s gland adenomas in two cats

Hines,

Giaretta,

Cavasin

et al. 2024

Journal of Feline Medicine and Surgery Open Reports

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Case series summary Two cats, aged 13.5 and 14 years, presented with duodenal masses ultimately diagnosed as Brunner’s gland (BG) adenomas. In the first cat, the lesion was a firm, pale tan, proximal duodenal polyp adjacent to the major duodenal papilla that was composed histologically of a well demarcated, expansile mass of well-differentiated BGs separated by fibrovascular septa and few adipocytes. This patient was euthanized for otitis-related vestibular signs, and the clinical significance of the duodenal polyp is unknown. The second cat presented with a 6-month history of vomiting. This cat had a mural duodenal mass in the region of the major duodenal papilla of approximately 2 cm, which was histologically composed of a dense population of variably ectatic BGs expanding the submucosa and lamina propria. This patient’s mass was non-resectable, but the vomiting resolved after palliative gastroenterostomy loop surgery to allow ingesta to flow past the mass. The patient survived 35 months after the procedure. Relevance and novel information BG adenoma is a rare, typically benign tumor in humans with non-specific clinical manifestations and no clear etiopathogenesis. This lesion, and the related condition BG hyperplasia, has been documented rarely in animals (one dog, two horses, and in mice and rats). This is the first description of the lesion in the cat. The comparative pathology, differential diagnoses and possible significance of these lesions are discussed.

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Section: Discussionmentioning

confidence: 99%

“…The histopathologic diagnosis of BG proliferative lesions may be difficult on endoscopy, as masses are contained within the submucosa and the size of endoscopic examples may preclude the identification of a mass effect. 3 , 6 , 8 The identification and description of a mass-like lesion is essential for the diagnosis.…”

Section: Discussionmentioning

confidence: 99%