Brucellosis-Induced Hemophagocytic Lymphohistiocytosis

Noumani, Jawahar Al; Busaidi, Ibrahim Al; Hajri, Malak Al

doi:10.7759/cureus.15677

Cited by 4 publications

(3 citation statements)

References 14 publications

(18 reference statements)

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“…Brucellosis-induced HPS has been described in literature [7][8][9][10][11][12][13] . It is difficult to diagnose Brucella melitensis infection because Brucella melitensis grows slowly in blood culturethe colonies will not be visible until at least three days later.…”

Section: Case Descriptionmentioning

confidence: 99%

“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

Song¹,

Xu²,

Li³

et al. 2019

Chinese Medical Sciences Journal

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Section: Case Descriptionmentioning

confidence: 99%

“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

Song¹,

Xu²,

Li³

et al. 2019

Chinese Medical Sciences Journal

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“…*p<0.01; CA: caries active; CF: caries-free; SD: standard deviation Some domains within CBCL of group I showed a negative correlation (Table4) 2024. Asundaria et al Cureus 16(4): e58648.…”

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confidence: 95%

Early Childhood Caries and Its Association With Behavior in Preschool Children

Asundaria,

Patil

2024

Cureus

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Background and aim Early childhood caries (ECC) is a profoundly impactful multifactorial condition that not only influences a child’s overall well-being but also diminishes their quality of life. Given the limited availability of literature on the relationship between children’s behavior and ECC, the present study utilized a standardized assessment tool to assess the association between ECC and behavioral changes in preschool children. Methodology Our study cohort consisted of 120 healthy preschool children, aged 18-60 months, evenly divided into two groups: caries-free (group I) and caries active (group II). Clinical features of ECC were meticulously inspected in each child, and the parents or caregivers completed the Child Behavior Checklist (CBCL), which comprises 100 questions related to a child’s daily behavior. The total scores, the narrow-band subscales, and raw scores were obtained. Accordingly, for each raw score, t-scores were obtained using the graphic display. These scores were then subjected to various statistical analyses including the Kolmogorov-Smirnov test, Mann-Whitney U test, and Spearman’s rank correlation method. Results Results of the present study revealed that there were no significant differences in behavior based on demographic factors such as gender and age. However notable differences were observed in several aspects of behavior between the two groups. Conclusion Caries-active children exhibited significantly higher levels of behavioral problems compared to their caries-free counterparts.

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“…10 The mechanism of brucellosis-associated thrombocytopenia is unclear and may be multifactorial, including immune destruction of platelets, secondary hemophagocytic lymphohistiocytosis, disseminated intravascular coagulopathy, bone marrow suppression, and hypersplenism. 11,12 Severe refractory thrombocytopenia secondary to brucellosis is rare.…”

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confidence: 99%

Treatment of Severe Refractory Thrombocytopenia in Brucellosis with Eltrombopag: A Case Report

Zhang

Ren

Huang

2022

Pediatric Infectious Disease Journal

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Brucellosis is a zoonotic disease. Severe refractory thrombocytopenia caused by brucellosis is very rare and easily misdiagnosed. We reported a 5-year-old girl who developed severe refractory thrombocytopenia secondary to brucellosis. The first-line treatment including corticosteroids and intravenous immunoglobulin did not elevate her platelets, but eltrombopag worked well and her platelet count recovered rapidly.

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Brucellosis-Induced Hemophagocytic Lymphohistiocytosis

Cited by 4 publications

References 14 publications

“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

Early Childhood Caries and Its Association With Behavior in Preschool Children

Treatment of Severe Refractory Thrombocytopenia in Brucellosis with Eltrombopag: A Case Report

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Brucellosis-Induced Hemophagocytic Lymphohistiocytosis

Cited by 4 publications

References 14 publications

&#x0201c;Typhoidal Cells&#x0201d; Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

&#x0201c;Typhoidal Cells&#x0201d; Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

Early Childhood Caries and Its Association With Behavior in Preschool Children

Treatment of Severe Refractory Thrombocytopenia in Brucellosis with Eltrombopag: A Case Report

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“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report

“Typhoidal Cells” Appear in a Woman with Hemophagocytic Syndrome Secondary To Brucellosis：A Case Report