Brucella suis Endocarditis

Golden, Bruce; Layman, Thomas E.; Koontz, Franklin P.; Mergner, W. J.

doi:10.1097/00007611-197004000-00011

Cited by 13 publications

(8 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Brucella suis, including biotype 2, has been reported with an increasing frequency as the causative agent of human disease (Chastel et al, 1970;Joubert et al, 1970;Golden et al, 1970;Heineman and Dziamski, 1976;Morris et al, 1979;Nadler et al, 1982;Thimm, 1982;Williams and Crossley, 1982;Francart et al, 1983;Teyssou et al, 1989;Bergeron et al, 1992;Robson et al, 1993;Kant et al, 1994;Paton et al, 2001;Kolbabová et al, 2001). We previously found Brucella antibodies in 5.2% of 524 adult women attending outpatient clinics and hospital in the Břeclav district in 1985-1986: one of these aborted, and another gave a premature birth to a baby with congenital malformation (microcephaly); because all other results of examination in these two women were negative, the symptoms might have been related to infection with B. suis biotype 2 (Hubálek et al, 1987).…”

Section: Discussionmentioning

confidence: 99%

Serological survey of the wild boar (Sus scrofa) for tularaemia and brucellosis in South Moravia, Czech Republic

Hubálek¹,

Treml²,

Juricová³

et al. 2002

Vet. Med.

View full text Add to dashboard Cite

Sera of 204 wild boars (Sus scrofa), shot by hunters in the South-Moravian district of Břeclav during 1993-2001, were tested by microagglutination reaction using safranin-stained antigens of Francisella tularensis and Brucella abortus: 10.8% and 8.7% seroreactors, respectively, were detected. The highest (17%) prevalence of tularaemia antibodies was found in wild boars during 1993-1994 at the beginning of a widespread outbreak of tularaemia in South Moravia that started in 1994, a nonsignificantly lower (13%) seroprevalence in 1995-1996 during the continuing epizootic, whereas it decreased markedly to 3% in the years 1997-2001 during the disappearance of the epizootic. Brucella sp. antibodies were significantly most frequent (15%) in wild boars in the years 1995-1996. This Brucella seroreactivity has been attributed to B. suis biotype 2 (B. melitensis biovar Suis biotype 2 according to new nomenclature) infection, because B. abortus in both cattle and humans (Bang's disease) was eradicated in the former Czechoslovakia in 1964. The hare brucellosis (B. suis biotype 2) has occurred in the Břeclav district in a number of natural foci revealing an increased activity since 1994.

show abstract

Section: Discussionmentioning

confidence: 99%

Serological survey of the wild boar (Sus scrofa) for tularaemia and brucellosis in South Moravia, Czech Republic

Hubálek¹,

Treml²,

Juricová³

et al. 2002

Vet. Med.

View full text Add to dashboard Cite

show abstract

“…This left us with 121 articles, with 308 analyzable cases. 77 of these articles are included in the references section [1–3, 7–80], and the full list of these articles can be obtained from the corresponding author.…”

Section: Methodsmentioning

confidence: 99%

“…Initially there was no clear evidence that antibiotics had any effect on the course of the disease as short courses of aureomycin, streptomycin, penicillin, and chloramphenicol all failed to be beneficial [5]. In 1955, the first successful treatment of Brucella abortus endocarditis using a long course of aureomycin and streptomycin was reported [6] and in 1966, for the first time, a case of severe Brucella suis endocarditis was treated surgically [7]. Since then, there have been reports of successful treatment with combined surgical and medical treatment [8–15].…”

Section: Introductionmentioning

confidence: 99%

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Keshtkar-Jahromi

Razavi

Gholamin

et al. 2012

The Annals of Thoracic Surgery

View full text Add to dashboard Cite

This review was undertaken to determine the role of surgery in the treatment of brucella endocarditis. All English and French articles reporting brucella endocarditis (1966–2011) in Pubmed, Google and Scopus were reviewed. 308 cases were identified and Linear and Logistic regression was performed. Surgery improved outcomes by decreasing mortality from 32.7% in the medical treatment only group to 6.7% in the combined surgical and medical treatment group (p<.001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients.

show abstract

“…Most patients had at least one regimen change during their course of therapy; in most cases the change in therapy was due to intolerance to the initial regimen, although treatment failure or relapse were the attributed causes in several cases. 26,27,41 Although length of therapy varied substantially, on average patients were treated for about 3 months.…”

Section: Case Presentationmentioning

confidence: 99%

“…The mortality rate in published cases is 21%, and many patients’ infection progressed despite adequate therapy. 32,41,50,52,55 A review of published cases suggested that several factors seem to be associated with increased likelihood of mortality with brucella arteritis. Survival seems to be lower in those infected with B suis than in those infected with other strains.…”

Section: Case Presentationmentioning

confidence: 99%

Brucella arteritis: clinical manifestations, treatment, and prognosis

Herrick

Lederman

Sullivan

et al. 2014

The Lancet Infectious Diseases

View full text Add to dashboard Cite

Brucellosis is the most common bacterial zoonosis, and causes a considerable burden of disease in endemic countries. Cardiovascular involvement is the main cause of mortality due to infection with Brucella spp., and most commonly manifests as endocarditis, peripheral and cerebrovascular aneurysms, or arterial and venous thrombosis. We report a case of brucellosis presenting as bacteremia and aortic endarteritis 18 years after the last known exposure to risk factors for brucella infection. The patient was treated with doxycycline, rifampin, and gentamicin, and underwent surgical repair of a penetrating aortic ulcer, with a good clinical recovery. We review the signs and symptoms, diagnostic approach, prognosis, and treatment of brucella arteritis. We draw attention to the absence of consensus about the optimum therapy for vascular brucellosis, and the urgent need for additional studies and renewed scientific interest in this major pathogen.

show abstract

Brucella suis Endocarditis

Cited by 13 publications

References 0 publications

Serological survey of the wild boar (Sus scrofa) for tularaemia and brucellosis in South Moravia, Czech Republic

Serological survey of the wild boar (Sus scrofa) for tularaemia and brucellosis in South Moravia, Czech Republic

Medical Versus Medical and Surgical Treatment for Brucella Endocarditis

Brucella arteritis: clinical manifestations, treatment, and prognosis

Contact Info

Product

Resources

About