Brucella glomerulonephritis resulting in end-stage renal disease: a case report and a brief review of the literature

Abstract

Brucella glomerulonephritis is a rare condition with only a few reported cases. We review the literature, and describe a 24-year-old female who presented with edema and proteinuria. Blood grew Brucella melitensis. Renal biopsy showed diffuse proliferative glomerulonephritis. The patient progressed to end-stage renal disease despite antibiotic and steroid therapy.

Renal biopsy findings in Iran: case series report from a referral kidney center

“…Anti-GBM 3/6 GS, glomerulosclerosis; GN, glomerulonephritis a As defined in text treatment of pharyngeal infections [4]. Additionally, GN with acute renal failure has been reported as a complication of other infections (e.g., by Brucella mellitensis or methicillin-resistant Staphylococcus aureus [33,34], and more prompt diagnosis and treatment of infectious diseases may have decreased the frequency of these glomerulonephritides. Comparing the frequency of MPGN between the report of Antonovych in 1983 and 1994 (14.8%) [12], our report on the first 407 patients (11.5%) [10] and the present study (5.5%), we observe a decrease in the incidence of MPGN (Fig.…”

The Case | Glomerulonephritis with prolonged recurrent fever

“…No crescents were found in these reports, and 6 cases were administered antibiotics combined with steroid therapy. 2 Our patient's renal biopsy revealed fibrous crescent and cellular fibroid crescent formations in the glomeruli and mononuclear cell infiltration in the interstitial area. Although his renal pathological changes were severe and associated with endocarditis, the patient clinically improved with antibiotic therapy without steroids.…”

Brucellosis presenting as myelofibrosis: First case report

“…Alternatively, myelofibrosis could occur secondary to an antibody-mediated autoimmune mechanism. 20 In support of this possibility is the positive Coombs' test, and the fact that brucellosis has been described with several autoimmune conditions such as glomerulonephritis, 21 Henoch-Schonlein purpura, 22 and thrombocytopenia. 23 In conclusion, this is the first report describing brucellosis complicated by myelofibrosis.…”