Brucella à l'aube du troisième millénaire : organisation du génome et pouvoir pathogène

Michaux‐Charachon, Sylvie; Foulongne, Vincent; O’Callaghan, David; Ramuz, M

doi:10.1016/s0369-8114(02)00313-9

Cited by 12 publications

(2 citation statements)

References 57 publications

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“…Brucellosis is caused by bacteria of the genus Brucella which contains twelve species [8,9,10]. Amongst the classical Brucella spp, B. abortus and B. melitensis are of paramount zoonotic importance worldwide, with small ruminants and cattle serving as preferential hosts [11].…”

Section: Introductionmentioning

confidence: 99%

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Mitterran

Barberine

Farikou

et al. 2020

Preprint

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Abstract Background: Brucellosis is an infectious disease caused by bacterial of the genus Brucella. Although investigations have identified Brucella antibodies in many animal species, little attention has been paid towards specific identification of different Brucella species in animals in Sub-Saharan African countries. This study was designed to identify Brucella abortus and Brucellla melitensis in cattle and sheep of several villages of southern Cameroon in order to improve our epidemiological knowledge on brucellosis in central AfricaMethods: Blood samples were collected from 597 cattle and 315 sheep from 15 villages of two regions of Cameroon. DNA was extracted from blood samples and primers amplifying the bcsp31 gene locus were used for the identification of Brucella spp infections in these animals. Amongst animals found with Brucella spp infections, specific primes were used to identify B. abortus and B. melitensis respectively. Results: Of the 912 animals analyzed in this study, 159 (17.4%) were infected with Brucella spp. This gives a Brucella infection rate of 20.9% in cattle and 10.8% in sheep. Of the 159 animals harboring Brucella spp infections, 119 (74.8%) were infected by B. abortus and 35 (22.0%) by B. melitensis. The overall infection rates were 18.4% (110/597) for B. abortus and 1.7% for B. melitensis in cattle; 2.9% for B. abortus and 7.9% for B. melitensis in sheep. Co-infections of B. abortus and B. melitensis were found in 9 (1%) animals; 6 (1%) cattle and 3 (1%) sheep. The Brucella infection rate was significantly higher in animals from the Noun division (20.6%) compared to those of Yoko (12.4%). Between animal species, significant differences (P = 0.0001) were observed in infection rates of both abortus and B. melitensis. Within and between sampling sites, significant differences (P = 0.02) were observed in the B. abortus infection rates. Conclusion: This study revealed B. melitensis and B. abortus infections in cattle and sheep from the Noun and Yoko divisions in southern Cameroon. The identification of B. melitensis and B. abortus in animals suggests further investigations on human brucellosis. Results of this study highlight the need of developing and implementing control measures against brucellosis in Cameroon.

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Section: Introductionmentioning

confidence: 99%

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Mitterran

Barberine

Farikou

et al. 2020

Preprint

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“…Brucellosis is one of the most widespread zoonotic infectious diseases in the world [1]. It is caused by bacteria of the genus Brucella which contains six species notably Brucella abortus, B. melitensis, B. suis, B. ovis, B. canis and B. neotomae [2,3]. This infectious disease is among the top thirteen neglected zoonotic and contagious diseases.…”

Section: Introductionmentioning

confidence: 99%

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Mitterran

Barberine

Farikou

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Brucellosis is an infectious disease caused by bacterial of the genus Brucella. Although several investigations detected Brucella antibodies in many animal species, low attention has been paid for specific identification of different Brucella species in animals of Sub-Saharan African counties. It is in this light that this study was designed to identify Brucella abortus and Brucellla melitensis in cattle and sheep of several villages of southern Cameroon in order to improve our epidemiological knowledge on brucellosis in central AfricaMethods: Blood samples were collected in 597 cattle and 315 sheep of 15 villages of two regions of Cameroon. DNA was extracted from blood samples and primers amplifying bcsp31 gene enabled the identification of Brucella spp infections in domestic animals. Amongst animals found with Brucella spp infections, specific primes were used to identify B. abortus and B. melitensis respectively. Results: From 912 animals analyzed in this study, 159 (17%) were found with Brucella infections. This gives an infection rate of 20.93% (125/597) in cattle and 10.79% (34/315) in sheep respectively. Of the 159 animals harboring Brucella infections, 118 (12.93%) were infected by B. abortus and 29 (3.17%) by B. melitensis. The Brucella infection rate (20.56%) was high in animals of the Noun division compared to those (12.35%) of Yoko. Between animal species, significant differences were observed in infection rates of both abortus and B. melitensis. The difference in the B. abortus infection rates remains significant between Yoko and Noun, and especially between villages of the Noun division. Conclusion: This study revealed for the first time B. melitensis and B. abortus infections in cattle and sheep of the Noun and Yoko in the southern Cameroon. The identification of B. melitensis and B. abortus in animals suggests further investigations on human brucellosis. Results of this study highlight the need of developing and implementing control measures against brucellosis in Cameroon, especially in villages presenting high risk for Brucella infections.

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Pathophysiology of Bone and Joint Infections

Frigui,

Chebbi,

Achour

2024

Histopathology of Bone and Joint Infections

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Brucella à l'aube du troisième millénaire : organisation du génome et pouvoir pathogène

Cited by 12 publications

References 57 publications

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Detection of Brucella abortus and Brucellla melitensis in cattle and sheep from southern Cameroon

Pathophysiology of Bone and Joint Infections

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