We revisit the problem of the overdamped (large friction) limit of the Brownian dynamics in an inhomogeneous medium characterized by a position-dependent friction coefficient and a multiplicative noise (local temperature) in one space dimension. Starting from the Kramers equation and analyzing it through the expansion in terms of eigenfunctions of a quantum harmonic oscillator, we derive analytically the corresponding Fokker-Planck equation in the overdamped limit. The result is fully consistent with the previous finding by Sancho, San Miguel, and Dürr [2]. Our method allows us to generalize the Brinkman's hierarchy, and thus it would be straightforward to obtain higher-order corrections in a systematic inverse friction expansion without any assumption. Our results are confirmed by numerical simulations for simple examples. The Brownian motion of a colloidal particle suspended in a spatially inhomogeneous medium is such an example. The medium inhomogeneity can be characterized, in general, by space dependence of the friction coefficient and the local temperature (or the diffusion coefficient). The naive Langevin description in the overdamped (large friction) limit led to the SDE with a multiplicative noise, which raised a question of the noise calculus choice, the so-called Ito-Stratonovich dilemma. However, it is clear that the corresponding underdamped Langevin equation does not depend on the noise calculus, thus the overdamped limit should not depend on it, either. This dilemma was settled down thirty years ago by Sancho, San Miguel, and Dürr (SSMD) [2] for most general cases. They successfully integrated out the fast variable (velocity) of the underdamped Langevin equation in the large friction limit by the so-called adiabatic elimination procedure, an extended version of the work done by Haken [3]. Interestingly, their results do not correspond to any choice of the noise calculus in the naive Langevin description, in general, except simple cases. However, this derivation is quite involved and mixes up the Langevin equation approach with the Fokker-Planck type description. And their results have never been tested against numerical simulations. These might cause some confusions, which triggered several recent works on this already resolved Ito-Stratonovich dilemma [4][5][6][7][8][9].For a simpler case with a constant friction coefficient (still space-dependent local temperature), the overdamped limit was rigorously derived by the FokkerPlanck equation approach [10] and also by the Langevin equation approach at the level of a single realization [11]. This case turns out to correspond to the naive Langevin description with the Ito calculus. The other simpler case with a space-dependent friction coefficient and a constant temperature was also studied and the FokkerPlanck equation in the overdamped limit was rigorously derived [12,13], which is equivalent to the naive Langevin description with the anti-Ito calculus. The overdamped limit for more general cases was rederived later by a singular perturbation theory ...