Brown tumour revealed: A literature review with a case study

Abstract

SummaryThe mandibular hyperparathyroid brown tumour is considered a rare metabolic disorder, also known as mandibular osteoclastome, therefore its therapy is not well defined yet; This lesion is triggered by the excess of the production of PTH parathyroid hormone, which are directly linked to mechanisms of control of levels of calcium, phosphorus and vitamin D, which confers the lesions the aspect of numerous osteoclastic cells, circumscribed and richly vascularised Which causes their reddish-brown coloration, individuals affected by this disorder show signs and symptoms of weakness, nausea, fatigue, anorexia, excessive thirst, polyuria, constipation and consequently depression, the purpose of this study is to perform a literature review by describing the case of mandibular brown tumour, explaining the conduct performed according to the case by clinical, laboratory analysis and image studies that guided the case.

Brown Tumor of Lower Right Limb in Patients With Primary Hyperparathyroidism: A Case Report

“…The findings of hyperparathyroidism were confirmed together with other exams to the diagnosis of Brown Tumour of Hyperparathyroidism. [4] Histological characteristics of brown tumor demonstrate highly vascular connective tissue with diffusely distributed multinucleated giant cells, and areas of hemorrhage and hemosiderin deposits 6. Skeletal demineralization, resulting from elevated plasma calcium, leads to multinucleated giant cells or osteoclasts replacing bone.…”