Brønsted Acid Promoted Facile Synthesis of Benzoacridines from Aromatic Aldehydes and N‐Phenyl Naphthylamines

Abstract

A facile method for the rapid synthesis of benzoacridines has been described. This protocol promoted by p-toluenesulfonic acid starts from aromatic aldehydes and N-phenyl naphthylamines, affording a variety of benzoacridines in 30 -90 % yields under metal-free conditions. The present approach involves a cascade of condensation, Friedel-Crafts alkylation, annulation and dehydroaromatization in one pot.