Bronchoscopy-Guided Topical Hemostatic Tamponade Therapy for the Management of Life-Threatening Hemoptysis

Valipour, Arschang; Kreuzer, A.; Koller, Hubert; Koessler, Wolfgang; Burghuber, Otto Chris

doi:10.1378/chest.127.6.2113

Cited by 129 publications

(66 citation statements)

References 23 publications

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“…The volume of expectorated blood has often been used to define episodes of massive hemoptysis, but no uniform cutoff value is agreed upon in the literature [1]. Amounts of expectorated blood ranging from 100 ml/24 h to more than 1,000 ml/24 h [2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19] have been proposed to define massive hemoptysis. Other terms, such as ‘major’ hemoptysis (≥200 ml/24 h) [4,14], severe hemoptysis (≥150 ml/12 h in de Gracia et al [10] and >400 ml/24 h in Khalil et al [19]) and ‘exsanguinating hemoptysis’ [11] (≥1,000 ml total or ≥150 ml/h) have also been employed to describe the extent of bleeding.…”

Section: Definitionmentioning

confidence: 99%

“…This more relevant definition relies on the main clinical consequences of hemoptysis: airway obstruction and hemodynamic instability. Examples of such a definition have included hemoptysis requiring transfusion [6], hospitalization [21], intubation [13,19] or causing aspiration and airway obstruction [11], hypoxemia (Pa O 2 <8 kPa or 60 mm Hg) [16] or death [21]. …”

Section: Definitionmentioning

confidence: 99%

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Massive Hemoptysis: An Update on the Role of Bronchoscopy in Diagnosis and Management

Sakr

Dutau²

2010

Respiration

223

187

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Hemoptysis is frequently encountered in clinical practice, and may be the presenting symptom of a number of diseases. Although massive hemoptysis accounts for only 5–15% of episodes, it should always be considered as a life-threatening condition that warrants effective assessment and management. In this article, we review the literature with regard to the definition, etiology, epidemiology, pathophysiology, diagnosis and treatment of massive hemoptysis, with special emphasis on the role of bronchoscopy as a diagnostic and therapeutic tool. We briefly present the circumstances under which the use of rigid bronchoscopy should be preferred for controlling massive bleeding. Moreover, we address the crucial importance of multidisciplinary collaboration by illustrating the roles of endovascular therapy and surgery in the optimal management of massive hemoptysis.

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Section: Definitionmentioning

confidence: 99%

Section: Definitionmentioning

confidence: 99%

Massive Hemoptysis: An Update on the Role of Bronchoscopy in Diagnosis and Management

Sakr

Dutau²

2010

Respiration

223

187

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“…As it is associated with high morbidity and mortality, surgery should be restricted to a minority of patients, such as in the event of BAE failure [27]. When experts in bronchoscopic management are available, bronchoscopic therapies may be used to control immediate bleeding [26,28]. However, long-term outcome data on these procedures is scarce, and further studies are warranted.…”

Section: Discussionmentioning

confidence: 99%

Severe haemoptysis in patients with nonsmall cell lung carcinoma

et al. 2014

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Severe haemoptysis due to nonsmall cell lung cancer (NSCLC) is considered a grim condition, and there is still scarce data on its characteristics and outcome, despite new imaging and treatment modalities. This retrospective study sought to describe the clinical characteristics, pathophysiology and outcome of NSCLC-related haemoptysis.We included 125 consecutive patients with severe haemoptysis (>100 mL) at admission, 65 (52%) exhibiting squamous cell carcinoma. Tumour cavitation/necrosis was reported in 26 (21%) patients. 52 patients had received anticancer treatment, but none had received anti-angiogenic agents.Severe haemoptysis was related mainly to the bronchial artery (82%), and major pulmonary artery involvement was rare (6.4%). Interventional radiology was performed in 102 patients. Bleeding cessation was achieved in 108 (87%) out of 125 patients. The overall in-hospital and 1-year survival rates were 69% and 30%, respectively. Performance status (PS) ⩾2 (OR 3.6, 95% CI 1.3-9.6), advanced stage (OR 8.6, 95% CI 2-37) and mechanical ventilation (OR 13, 95% CI 4.5-36) were independent predictors of in-hospital mortality. Performance status ⩾2 (hazard ratio (HR) 2.4, 95% CI 1.5-3.7), advanced stage (HR 4, 95% CI 2.1-7.7), cancer progression (HR 2, 95% CI 1.01-2.7) and cavitation/necrosis (HR 1.7, 95% CI 1.21-3.2) were independently associated with 1-year mortality.Management of severe haemoptysis related to NSCLC should be improved, given our observed survival rates after hospital discharge. @ERSpublications NSCLC-related haemoptysis should not be considered dismissively; its management is still suboptimal

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“…Bronkoskopun çalışma kanalından girilerek kanama odağının soğuk serum fizyolojikle veya adrenalinli serum fizyolojikle yıkanması, kanama odağına balon tamponatı uygulanması, stent veya silikon tıkaç ile tamponat uygulaması, kanama odağının elektrokoter, lazer, argon plazma veya kriyoterapi yön-temlerinden biriyle koagüle edilmesi gibi yöntemlerle bronkoskopik hemoptizi tedavisi mümkündür (2,(11)(12)(13)(14).…”

Section: Hemopti̇zi̇ Tedavi̇si̇nde Bronkoskopi̇k Uygulamalarunclassified

Bronchoscopic Interventions in Patients With Hemoptysis

Bostancı¹

2015

Toraks Cer Bult

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Bronchoscopy-Guided Topical Hemostatic Tamponade Therapy for the Management of Life-Threatening Hemoptysis

Cited by 129 publications

References 23 publications

Massive Hemoptysis: An Update on the Role of Bronchoscopy in Diagnosis and Management

Massive Hemoptysis: An Update on the Role of Bronchoscopy in Diagnosis and Management

Severe haemoptysis in patients with nonsmall cell lung carcinoma

Bronchoscopic Interventions in Patients With Hemoptysis

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