Bronchoscopic finding determined outcome after chemoradiotherapy in esophageal cancer patients with airway invasion

Yin, Shun-Ying; Chao, Yin‐Kai; Tseng, Chen‐Kan; Chang, Hsien‐Kun; Liu, Yun-Hen; Wu, Yi‐Cheng; Chen, Tzu-Ping; Yeh, Chi-Ju

doi:10.1002/jso.23578

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…There are several studies that investigated the location of airway involvement, which may be associated with unfavorable outcome. Yin et al 18 found that an esophageal tumor that involved the carina was one of the predictors for poor survival. Because of the anatomical complexity of the carina, bronchoscopic intervention could be challenging and it is sometimes difficult to select the appropriate stent for airway restoration.…”

Section: Discussionmentioning

confidence: 99%

The Prognostic Predictors of Airway Stenting in Malignant Airway Involvement From Esophageal Carcinoma

Leelayuwatanakul

Thanthitaweewat

Wongsrichanalai

et al. 2022

Journal of Bronchology &Amp; Interventional Pulmonology

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Background: In locoregional esophageal carcinoma (EC), airway involvement is the most common route of extraesophageal metastasis. The prognosis remains poor even with a multimodality approach. Although airway stenting is well known for restoration of the airway, the survival benefit is still lacking. Methods: A total of 37 of patients with airway involvement from EC who underwent airway stenting at a single institution from 2015 to 2020 were retrospectively reviewed. Survival curves after stent placement among different groups were analyzed using Kaplan-Meier method. Results: Of 37 patients, 34 were male, and the mean age was 58.9 years (42 to 80). EC was commonly located at midesophagus (51.4%). The site of airway involvement was left main bronchus (48.6%), trachea (32.4%), multiple sites (16.2%), and right main bronchus (2.7%). The nature of airway involvement was tumor invasion (91.9%), compression (62.2%), and fistula (37.8%). Twenty-three patients (62.2%) had airway involvement at the time of esophageal cancer diagnosis. Only 4 patients underwent esophageal stenting. The median survival time after stent placement was 97 days (5 to 539). Chemotherapy and/or radiotherapy were given before stent placement in 18 patients (48.6%). Treatment-naive before airway stenting and diagnosis of airway involvement at the same time of EC diagnosis were independent predictors for the increased survival after stent placement (P<0.05). Poststent treatment was associated with improved survival (P=0.002). Conclusion: In patients with malignant airway involvement from EC who underwent airway stenting, the prognostic predictors for improved survival were treatment-naive status, receiving treatment after airway stenting, and early-onset of airway involvement.

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Section: Discussionmentioning

confidence: 99%

The Prognostic Predictors of Airway Stenting in Malignant Airway Involvement From Esophageal Carcinoma

Leelayuwatanakul

Thanthitaweewat

Wongsrichanalai

et al. 2022

Journal of Bronchology &Amp; Interventional Pulmonology

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Efficacy and Safety of Induction Chemotherapy in Esophageal Cancer with Airway Involvement

Noronha

Joshi

Patil

et al. 2016

J Gastrointest Canc

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Bronchoscopic finding determined outcome after chemoradiotherapy in esophageal cancer patients with airway invasion

Abstract: Bronchoscopic finding determined outcome after CRT in esophageal cancer patients with airway invasion.

Cited by 2 publications

References 15 publications

The Prognostic Predictors of Airway Stenting in Malignant Airway Involvement From Esophageal Carcinoma

The Prognostic Predictors of Airway Stenting in Malignant Airway Involvement From Esophageal Carcinoma

Efficacy and Safety of Induction Chemotherapy in Esophageal Cancer with Airway Involvement

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