Bronchoscopic and Radiologic Features of Kaposi's Sarcoma Involving the Respiratory System

Zibrak, Joseph D.; Silvestri, Ronald C.; Costello, Philip; Marlink, Richard; Jensen, William A.; Robins, Arthur; Rose, Richard M.

doi:10.1378/chest.90.4.476

Cited by 82 publications

(44 citation statements)

References 17 publications

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“…Some clinical studies have shown a higher prevalence in individuals with AIDS who already had the cutaneous form of the disease (over 32%) compared to those without it (3-13%). 3,[9][10][11] In autopsies, however, bronchopulmonary KS was found in 47% of patients with AIDS who had the cutaneous form, which reveals a possible underdiagnosis of pulmonary involvement. 12 Since the variety of opportunistic diseases is great, pulmonary involvement in SK can be difficult to diagnose.…”

Section: Introductionmentioning

confidence: 99%

“…Thoracic involvement may include trachea, lymph vessels, pleura and lung parenchyma. 2,3 case report J.M.S., 35, female, admitted into Hospital Barão de Lucena due to the presence of purplish lesions on the face, trunk, limbs, palate and right external ear, episodes of selflimiting diarrhea, and weight loss of approximately 15 kg in the course of approximately 9 months. AIDS diagnosis was made based on rapid HIV testing with serologic confirmation by ELISA.…”

Section: Introductionmentioning

confidence: 99%

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Pulmonary Kaposi’s sarcoma in a female patient: Case report

Petribu¹,

Cisneiros²,

Carvalho³

et al. 2016

Rev. Assoc. Med. Bras.

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SUMMARY Kaposi’s sarcoma (KS) is a multicentric lymphoproliferative malignancy. Most of the time this tumor is confined to the skin and subcutaneous tissue, but it can present with widespread visceral involvement, such as in the lung. Pulmonary KS is the most frequent form in young adult males, in a ratio of 15:1. The disease usually affects individuals with low CD4 lymphocyte counts (<150-200 cells/mm3). We report a case of a female patient aged 35 years, with the presence of skin lesions, self-limiting episodes of diarrhea and weight loss of 15 kg for nearly 9 months, progressing to persistent fever. AIDS was diagnosed and biopsy of the lesions revealed Kaposi’s sarcoma. Computed tomography of the chest showed peribronchovascular thickening, areas of ground glass opacity, condensations with air bronchograms surrounded by ground glass opacity (halo sign) and bilateral pleural effusion. The diagnosis of pulmonary KS is still a challenge, especially due to the occurrence of other opportunistic diseases that may also occur concurrently. Therefore, suspecting this diagnosis based on clinical and laboratory manifestations, and even more with CT findings, is fundamental, especially in patients who already have the cutaneous form of the disease.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Pulmonary Kaposi’s sarcoma in a female patient: Case report

Petribu¹,

Cisneiros²,

Carvalho³

et al. 2016

Rev. Assoc. Med. Bras.

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“…"In the multivariate analysis, staging (T1), CD4 cell count (<200 cells/µl), [and] positive HHV8 DNA in plasma, at the time of diagnosis, predict evolution towards death or the need of chemotherapy." 8 Kaposi's sarcoma has also been found to present in the lungs 9 , which is a possible manifestation for this patient. Additionally, the patient's symptoms of SOB and fatigue have appeared in other patients with pulmonary Kaposi's sarcoma.…”

Section: Discussionmentioning

confidence: 60%

A Kaposi black eye

Gibler

Thakolwiboon²,

Iwuji³

et al. 2018

The Chronicles

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“…Its clinical and radiographic presentation may mimic pneumonia due to opportunistic infections, although nodular infiltrates and intrathoracic lymph node enlargement are commonly seen. Because pleural effusion only rarely occurs in patients with opportunistic infections, such as Peunonocystis carinii, the presence of pleural effusion in a patient with cutaneous KS suggests the diagnosis of pulmonary KS [8].…”

Section: Introductionmentioning

confidence: 99%

Bilateral Chylothorax. An Unusual Presentation in the Course of Immune Reconstitution Inflammatory Syndrome, HIV Infection and Kaposi’s Sarcoma: A Case Report

Boultadakis

2014

J Med Cases

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Immune reconstitution inflammatory syndrome (IRIS) is a term used to describe the paradoxical worsening of a pre-existing infection or the presentation of a previously undiagnosed condition in HIV-infected patients soon after commencement of antiretroviral therapy (ART). We report a case of a patient with HIV infection and Kaposi sarcoma, who developed bilateral chylothorax as a manifestation of IRIS, after the initiation of highly active antiretroviral therapy. Bilateral chylothorax is extremely rare and has been associated with significant morbidity and mortality. We present here the successful management with bilateral video-assisted thoracic surgery.

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Bronchoscopic and Radiologic Features of Kaposi's Sarcoma Involving the Respiratory System

Cited by 82 publications

References 17 publications

Pulmonary Kaposi’s sarcoma in a female patient: Case report

Pulmonary Kaposi’s sarcoma in a female patient: Case report

A Kaposi black eye

Bilateral Chylothorax. An Unusual Presentation in the Course of Immune Reconstitution Inflammatory Syndrome, HIV Infection and Kaposi’s Sarcoma: A Case Report

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