Bronchopulmonary Dysplasia: a Modern View on Course and Outcomes

Казакова, К. А.

doi:10.15690/pf.v13i4.1609

Pediatr. farmakol.

2016

DOI: 10.15690/pf.v13i4.1609

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Bronchopulmonary Dysplasia: a Modern View on Course and Outcomes

К. А. Казакова

Abstract: ВВЕДЕНИЕБронхолегочная дисплазия (БЛД) -полиэтиологич-ное хроническое заболевание морфологически незрелых легких, развивающееся у новорожденных, главным обра-зом глубоко недоношенных детей, получающих кисло-родотерапию и находящихся на искусственной вентиля-ции легких (ИВЛ). Клиническая картина характеризуется преимущественным поражением бронхиол и паренхимы легких, развитием эмфиземы, фиброза и/или нарушени-ем репликации альвеол, кислородозависимостью в воз-расте 28 сут жизни и старше, бронхообструктивным син… Show more

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Cited by 2 publications

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Information value of ante- and intranatal risk factors for bronchopulmonary dysplasia in preterm newborns

Agarkov

Kicha

Блинков

et al. 2019

Ross. vestn. perinatol. pediatr.

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Aim of the study. To identify the leading antenatal and intranatal risk factors for bronchopulmonary dysplasia based on the analysis of their prevalence and information content Materials and methods. We performed a prospective follow-up of 124 infants of gestational age of less than 32 weeks with the classical form of bronchopulmonary dysplasia (study group). The control group included 119 newborns with gestational age of less than 32 weeks without bronchopulmonary dysplasia. The parents of the compared groups were questioned, with the following assessment of the prevalence and informative value of antenatal and intranatal risk factors. Results. The leading antenatal and intranatal risk factors for the development of bronchopulmonary dysplasia are: acute respiratory viral infection in II-III trimester, threatened miscarriage, intrauterine growth retardation, Apgar score at the 1st (3 or less) and 5th minute (5 or less), body weight of less than 1400g at birth, body length less than 36 cm at birth, cesarean section, more then 6-hours waterless period. Conclusion. The combination of these intranatal and antenatal risk factors can be attributed to a group with high risk of bronchopulmonary dysplasia.

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Information value of ante- and intranatal risk factors for bronchopulmonary dysplasia in preterm newborns

Agarkov

Kicha

Блинков

et al. 2019

Ross. vestn. perinatol. pediatr.

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The capability of chest computed tomography in the diagnosis of bronchopulmonary dysplasia outcomes in premature infants

Павлинова¹,

Киршина²,

Сахипова³

et al. 2019

Med. sov.

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Purpose of the study was to establish clinical and radiological features of bronchopulmonary dysplasia (BPD) outcomes in children. Materials and methods. A prospective follow-up study of 132 premature infants with infant respiratory distress syndrome (IRDS) was analyzed. BPD was developed in 66 cases. At a late childhood, clinical and radiological outcomes of the transferred conditions were diagnosed on the basis of anamnesis, clinical examination, and results of chest computed tomography (CT). Results. Clinical recovery was observed significantly more frequently in the outcome of IRDS without BPD development (69.6% versus 31.8% in the case of BPD development). In patients with BPD in the anamnesis, the odds ratio of asthma developed in the late childhood was 5.304 times higher than in children who had IRDS. The majority (62 cases, 93.9%) of children who had IRDS did not have structural changes in lung tissue according to CT (p = 0.000), 21 (31.8%) children with BPD had abnormal CT. In BPD, typical radiological findings were hypoattenuated lung areas (p = 0.020) and areas of pulmonary fibrosis (p = 0.016). Conclusion. Chest CT could be assigned to the patients with BPD in the anamnesis to assess lung tissue structural changes and diagnose outcomes of the disease.

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Bronchopulmonary Dysplasia: a Modern View on Course and Outcomes

Cited by 2 publications

References 53 publications

Information value of ante- and intranatal risk factors for bronchopulmonary dysplasia in preterm newborns

Information value of ante- and intranatal risk factors for bronchopulmonary dysplasia in preterm newborns

The capability of chest computed tomography in the diagnosis of bronchopulmonary dysplasia outcomes in premature infants

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