Bronchopulmonary circulation in d-transposition of the great arteries: Possible role in genesis of accelerated pulmonary vascular disease

Aziz, Kalim U.; Paul, Milton H.; Rowe, Richard D.

doi:10.1016/s0002-9149(77)80101-x

Cited by 34 publications

(7 citation statements)

References 29 publications

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“…Collateral vessels were held theoretically to develop to the underperfused lung. Such vessels were described by Aziz et al, 3 and later by Wernovsky et al 4 The report of enlarged bronchial arteries after early repair of complete transposition by Wernovsky et al 4 suggests that these abnormal vessels are frequently found at postoperative catheterization despite early repair.…”

Section: Discussionmentioning

confidence: 90%

Preferential flow to the right pulmonary artery after an early arterial switch procedure

1996

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Despite early arterial switch repair of complete transposition of the great vessels, significant physiologic aberrations may still occur. Two cases of vascular disease in the left pulmonary arterial system are described and potential mechanisms are discussed. We conclude a small number of children with simple transpostion may develop asymmetric patterns of pulmonary blood flow without evidence of anatomic narrowing of either arterial vessel.

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Section: Discussionmentioning

confidence: 90%

Preferential flow to the right pulmonary artery after an early arterial switch procedure

1996

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“…The association between the transposition of the great arteries and pulmonary artery growth has been suggested in published reports relating it to accelerated pulmonary vasculopathy and asymmetric distribution of the pulmonary blood flow 12,13 …”

Section: Discussionmentioning

confidence: 99%

The behavior of residual pulmonary artery gradient after arterial switch operation: A longitudinal data analysis

Alkattan

Diraneyya

Elmontaser

et al. 2020

Journal of Cardiac Surgery

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Objective: The arterial switch operation (ASO) is the standard treatment for the transposition of the great arteries. The timely variation in the residual pressure gradient across the pulmonary arteries is ill-defined. This study is aimed to study the progressive changes in the pressure gradient across the pulmonary valve and pulmonary arteries after ASO. Methods: All eligible patients for this study who underwent ASO between 2000 and 2019 were reviewed. Transthoracic echocardiography was used to estimate the peak pressure gradient across the pulmonary artery and its branches. The primary outcome was the total peak pressure gradient (TPG) which is the sum of peak pressure gradients across the main pulmonary artery and pulmonary artery branches. Furthermore, longitudinal data analyses with mixed-effect modeling were used to determine the independent predictors for the changes in the pressure gradient. Results: Three hundred and nine patients were included in the study. Over a 17-year follow-up, the freedom from pulmonary stenosis reintervention was 95% (16 out of the 309 patients underwent reintervention = 5%). The longitudinal data analyses of serial 1844 echocardiographic studies for the included patients revealed that the TPG recorded in the first postoperative echocardiogram across pulmonary valve, right and left pulmonary artery branches was the most significant predictor for reintervention. Conclusion: The total peak gradient measured in the first postoperative echocardiogram is the most important predictor for reintervention. We propose that a total peak gradient in the first postoperative echocardiography of 55 mm Hg or more is a predictor for reintervention.

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Section: Regarding Limited Buttons Resection Technique a Data Of 120mentioning

confidence: 98%

The behavior of residual pulmonary artery gradient after arterial switch operation: A longitudinal data analysis

Alkattan

Diraneyya

Elmontaser

et al. 2020

Preprint

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Objective: The arterial switch operation is the standard treatment for the transposition of the great arteries. The timely variation in the residual pressure gradient across the pulmonary arteries is ill-defined. This work is aimed to study the progressive changes in the pressure gradient across the pulmonary valve and pulmonary arteries after arterial switch operation (ASO). Methods: All eligible patients for this study who underwent arterial switch operation between 2000 and 2019 were reviewed. Transthoracic echocardiography (TTE), was used to estimate the peak pressure gradient across the pulmonary artery and its branches. The primary outcome was the total peak pressure gradient (TPG) which is the sum of peak pressure gradients across the main pulmonary artery and pulmonary artery branches. Furthermore, a longitudinal data analyses with mixed effect modeling were used to determine the independent predictors for the changes in pressure gradient. Results: 309 patients were included in the study. Over 17-year follow up, the freedom from pulmonary stenosis reintervention was 95% (16 out of the 309 patients underwent reintervention = 5%). the Longitudinal data analyses of serial 1844 echocardiographic studies for the included patients revealed that the TPG recorded in the first postoperative echocardiogram across pulmonary valve, right and left pulmonary artery branches was the most significant predictor for reintervention. Conclusion: The total peak gradient measured in the first postoperative echocardiogram is the most important predictor for reintervention. We propose that a total peak gradient in the first postoperative echocardiography of 55 mmHg or more is a predictor for reintervention The behavior of residual pulmonary artery gradient after arterial switch operation: A longitudinal data analysis ABSTRACT Objective: The arterial switch operation is the standard treatment for the transposition of the great arteries. The timely variation in the residual pressure gradient across the pulmonary arteries is ill-defined. This work is aimed to study the progressive changes in the pressure gradient across the pulmonary valve and pulmonary arteries after arterial switch operation (ASO). Methods: All eligible patients for this study who underwent arterial switch operation between 2000 and 2019 were reviewed. Transthoracic echocardiography (TTE), was used to estimate the peak pressure gradient across the pulmonary artery and its branches. The primary outcome was the total peak pressure gradient (TPG) which is the sum of peak pressure gradients across the main pulmonary artery and pulmonary artery branches. Furthermore, a longitudinal data analyses with mixed effect modeling were used to determine the independent predictors for the changes in pressure gradient. Results: 309 patients were included in the study. Over 17-year follow up, the freedom from pulmonary stenosis reintervention was 95% (16 out of the 309 patients underwent reintervention = 5%). the Longitudinal

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Bronchopulmonary circulation in d-transposition of the great arteries: Possible role in genesis of accelerated pulmonary vascular disease

Cited by 34 publications

References 29 publications

Preferential flow to the right pulmonary artery after an early arterial switch procedure

Preferential flow to the right pulmonary artery after an early arterial switch procedure

The behavior of residual pulmonary artery gradient after arterial switch operation: A longitudinal data analysis

The behavior of residual pulmonary artery gradient after arterial switch operation: A longitudinal data analysis

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